Results 81 to 90 of about 898,388 (199)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Análisis de los tiempos de la gestión editorial en revistas colombianas de Ciencias de la Salud, indexadas en SCImago Journal & Country Rank (SJR), 2017

open access: yesSalud Uninorte, 2019
Objetivo: Este estudio pretende analizar los tiempos de la gestión editorial en las revistas colombianas de Ciencias de la Salud indexadas en Scimago (SJR), año 2017.Método: Consistió en la revisión de 782 artículos publicados en las 18 revistas de ...
OSKARLY PÉREZ ANAYA   +5 more
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Revisión de los trabajos originales que analizan el impacto de la contaminación atmosférica sobre la mortalidad, 1994-1998

open access: yesRevista Española de Salud Pública, 1999
Se revisan los diferentes estudios publicados e indexados en Medline y el Indice Médico Español (IME) desde el año 1984 hasta el año 1998 (IME: desde 1971 a 1996). En una primera fase se evaluó la producción cuantitativa de publicaciones que versan sobre
Tenías Burillo José Mª   +3 more
doaj  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Review of health research on indigenous populations in Latin America, 1995-2004 Revisión de la investigación en salud en poblaciones indígenas de Latinoamérica, 1995-2004

open access: yesSalud Pública de México, 2007
OBJECTIVE: To review health research conducted among indigenous populations in Latin America during the period 1995-2004. Material and methods. The search strategy was purposely broad to ensure the identification of all relevant studies indexed in the ...
Miguel San Sebastián, Anna-Karin Hurtig
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Avaliação da qualidade de vida após síndrome coronariana aguda: revisão sistemática

open access: yesArquivos Brasileiros de Cardiologia, 2011
Suzana Alves da Silva   +3 more
doaj   +1 more source

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