Results 51 to 60 of about 19,439 (263)

Revitalize the world’s countryside [PDF]

open access: yesNature, 2017
A rural revival is needed to counter urbanization across the globe, say Yansui Liu and Yuheng Li.
Yansui, Liu, Yuheng, Li
openaire   +2 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin   +11 more
wiley   +1 more source

Environmental regulation and bioenergy production: a case study of China’s pig farms

open access: yesFrontiers in Sustainable Food Systems
Transforming livestock waste into bioenergy represents a critical pathway for the circular economy, simultaneously addressing environmental pollution and fostering the clean energy transition.
Dingqiang Sun   +3 more
doaj   +1 more source

A Millimeter‐Scale Implantable Magneto–Mechano–Electric Transducer Based on BTO Piezoelectric Ceramics for Remote Wireless Electrical Stimulation of Injured Sciatic Nerves

open access: yesAdvanced Science, EarlyView.
We report a fully wireless, circuit‐free neural stimulator built on a millimetric magneto‐mechano‐electric (MME) cantilever transducer (3 × 10 × 5 mm) with a barium titanate (BTO) piezoelectric ceramic core. Under low‐frequency alternating magnetic fields, the MME cantilever mechanically oscillates, inducing stress on the BTO element and thereby ...
Yijing Wang   +7 more
wiley   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao   +8 more
wiley   +1 more source

Greening the countryside: The unexpected role of returning entrepreneurship in agricultural carbon mitigation

open access: yesInternational Review of Economics & Finance
Greenhouse gas emissions from the agricultural sector are a significant contributor to global climate change. As a novel driving force integrating multiple resources, returning entrepreneurship may offer a critical pathway for low-carbon agricultural ...
Xing Ji, Xiaomin Li, Yijun Peng
doaj   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

Empowering the underprivileged in China: how does information accessibility affect their entrepreneurship?

open access: yesHumanities & Social Sciences Communications
Entrepreneurship and employment are crucial sources of sustainable livelihoods for underprivileged populations, but the availability of information shapes their entrepreneurship.
Shanqing Liu   +4 more
doaj   +1 more source

The Politics of Labour Movement Revitalization: The Need for a Revitalized Perspective [PDF]

open access: yesEuropean Journal of Industrial Relations, 2003
One important common theme of our five-country research is that all union movements see political engagement as essential in their efforts at revitalization. Specific forms of political action, however, vary according to national context. If unions find or build adequate political and institutional supports, they have less incentive to mobilize the ...
Baccaro, Lucio   +2 more
openaire   +3 more sources

Multi‐Stimuli Responsive Viologen‐Crosslinked Eutectogels Derived From Natural Deep Eutectic Solvents for Information Security and Motion Detection

open access: yesAdvanced Science, EarlyView.
Described herein is the development of an organic eutectic gel based on a deep eutectic mixture of naturally derived betaine and lactic acid. The eutectic gels exhibit reversible color‐switching in response to multiple stimuli including strain, UV light, and temperature, enabling advanced applications in information security, intelligent wearable ...
Zhiang Bai   +3 more
wiley   +1 more source

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