Results 81 to 90 of about 257,307 (293)

Neuroadaptive Changes Associated with Smoking: Structural and Functional Neural Changes in Nicotine Dependence

Brain Sciences, 2013
Tobacco smoking is the most frequent form of substance abuse. We provide a review of the neuroadaptive changes evidenced in human smokers with regard to the current neurobiological models of addiction.
Chantal Martin-Soelch
doaj   +1 more source

Early childhood stress exposure, reward pathways, and adult decision making [PDF]

, 2017
Rasmus M. Birn, Barbara J. Roeber, Seth D. Pollak   +2 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Reward Model Perspectives: Whose Opinions Do Reward Models Reward?

Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing
Published at EMNLP 2025 under the full author name "Elle"
openaire   +3 more sources

Maximizing throughput in NOMA-enable industrial IoT networks using digital twin and reinforcement learning

Journal of Advanced Research
Introduction: Increased deployment of heterogeneous and complex Industrial Internet of Things (IIoT) applications such as predictive maintenance and asset tracking places a substantial strain on the limited computational and communication resources.
Sekione Reward Jeremiah, David Camacho, Jong Hyuk Park   +2 more
doaj   +1 more source

Genetic Relationships Between Ethanol-Induced Conditioned Place Aversion and Other Ethanol Phenotypes in 15 Inbred Mouse Strains

Brain Sciences, 2019
The genetic relationships between different behaviors used to index the aversive effects of ethanol are unknown. To address this issue, ethanol-induced conditioned place aversion (CPA) was tested in a genetically diverse panel of 15 inbred mouse strains.
Christopher L. Cunningham
doaj   +1 more source

Scaling prediction errors to reward variability benefits error-driven learning in humans [PDF]

, 2015
Kelly Diederen, Wolfram Schultz
openalex   +1 more source

Configurable Agent With Reward As Input: A Play-Style Continuum Generation [PDF]

, 2021
Pierre Le Pelletier de Woillemont, Rémi Labory, Vincent Corruble   +2 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

An Update on the Role of Serotonin and its Interplay with Dopamine for Reward

Frontiers in Human Neuroscience, 2017
The specific role of serotonin and its interplay with dopamine (DA) in adaptive, reward guided behavior as well as drug dependance, still remains elusive.
Adrian G. Fischer, Adrian G. Fischer, Markus Ullsperger, Markus Ullsperger   +3 more
doaj   +1 more source