Results 81 to 90 of about 1,393,287 (284)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The link between social comparison orientation and domain-specific risk-taking: exploring the mediating role of two dimensions of trait competitiveness

open access: yesFrontiers in Psychology
IntroductionOur recent research has demonstrated that social comparison orientation of ability (SCO-ability) is an antecedent of trait competitiveness (TC), and TC mediates the relation between SCO-ability and domain-specific risk-taking.
Yuqian Wang   +5 more
doaj   +1 more source

Learning the specific quality of taste reinforcement in larval Drosophila

open access: yeseLife, 2015
The only property of reinforcement insects are commonly thought to learn about is its value. We show that larval Drosophila not only remember the value of reinforcement (How much?), but also its quality (What?).
Michael Schleyer   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Exploring the relationship between employee engagement and counterproductive work behaviour

open access: yesFrontiers in Psychology
IntroductionDespite the cumulative increase in counterproductive work behaviour in various organisations which have ripple effects on general organisational performance, little is known on how employee engagement relates to counterproductive work ...
Sphindile Mvuyana   +2 more
doaj   +1 more source

Sequential selection of economic good and action in medial frontal cortex of macaques during value-based decisions

open access: yeseLife, 2015
Value-based decisions could rely either on the selection of desired economic goods or on the selection of the actions that will obtain the goods. We investigated this question by recording from the supplementary eye field (SEF) of monkeys during a ...
Xiaomo Chen, Veit Stuphorn
doaj   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

Primate amygdala neurons evaluate the progress of self-defined economic choice sequences

open access: yeseLife, 2016
The amygdala is a prime valuation structure yet its functions in advanced behaviors are poorly understood. We tested whether individual amygdala neurons encode a critical requirement for goal-directed behavior: the evaluation of progress during ...
Fabian Grabenhorst   +2 more
doaj   +1 more source

Dopamine promotes instrumental motivation, but reduces reward-related vigour

open access: yeseLife, 2020
We can be motivated when reward depends on performance, or merely by the prospect of a guaranteed reward. Performance-dependent (contingent) reward is instrumental, relying on an internal action-outcome model, whereas motivation by guaranteed reward may ...
John P Grogan   +3 more
doaj   +1 more source

High reward enhances perceptual learning. [PDF]

open access: yes, 2018
Studies of perceptual learning have revealed a great deal of plasticity in adult humans. In this study, we systematically investigated the effects and mechanisms of several forms (trial-by-trial, block, and session rewards) and levels (no, low, high ...
Chen, Ge   +12 more
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