Results 71 to 80 of about 1,394,868 (297)

A causal role for right temporo-parietal junction in signaling moral conflict

open access: yeseLife, 2018
The right temporo-parietal junction (rTPJ) has been proposed to play a key role in guiding human altruistic behavior, but its precise functional contribution to altruism remains unclear.
Ignacio Obeso   +3 more
doaj   +1 more source

The Effects of Non-Contingent Extrinsic and Intrinsic Rewards on Memory Consolidation [PDF]

open access: yes, 2005
Emotional and arousing treatments given shortly after learning enhance delayed memory retrieval in animal and human studies. Positive affect and reward induced prior to a variety of cognitive tasks enhance performance, but their ability to affect memory ...
Bryant, Ted, Nielson, Kristy A.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Neurocomputational mechanisms involved in adaptation to fluctuating intentions of others

open access: yesNature Communications
Humans frequently interact with agents whose intentions can fluctuate between competition and cooperation over time. It is unclear how the brain adapts to fluctuating intentions of others when the nature of the interactions (to cooperate or compete) is ...
Rémi Philippe   +5 more
doaj   +1 more source

Reward positivity elicited by predictive cues

open access: yes, 2011
A recent theory holds that a component of the human event-related brain potential called the reward positivity reflects a reward prediction error signal. We investigated this idea in gambling-like task in which, on each trial, a visual stimulus predicted
Holroyd, Clay   +2 more
core   +1 more source

Distributed Online Learning via Cooperative Contextual Bandits [PDF]

open access: yes, 2015
In this paper we propose a novel framework for decentralized, online learning by many learners. At each moment of time, an instance characterized by a certain context may arrive to each learner; based on the context, the learner can select one of its own
Tekin, Cem, van der Schaar, Mihaela
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Socially-Aware Incentive Mechanism for Mobile Crowdsensing Service Market

open access: yes, 2018
Mobile Crowdsensing has shown a great potential to address large-scale problems by allocating sensing tasks to pervasive Mobile Users (MUs). The MUs will participate in a Crowdsensing platform if they can receive satisfactory reward.
Luo, Jun   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Commentary: New View on Treatment of Drug Dependence

open access: yesBasic and Clinical Neuroscience, 2014
In the 1960s, discovery of pleasure system (defined as reward system) in the brain that may underlie drug reward and addiction encouraged many scientists to investigate the mechanisms by which drug abuse affects central nervous system function.
Mina Ranjbaran, Hedayat Sahraei
doaj  

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