Results 81 to 90 of about 1,394,868 (297)

Language Learning Enhanced by Massive Multiple Online Role-Playing Games (MMORPGs) and the Underlying Behavioral and Neural Mechanisms

Frontiers in Human Neuroscience, 2017
Massive Multiple Online Role-Playing Games (MMORPGs) have increased in popularity among children, juveniles, and adults since MMORPGs’ appearance in this digital age.
Yongjun Zhang, Yongjun Zhang, Hongwen Song, Xiaoming Liu, Xiaoming Liu, Dinghong Tang, Yue-e Chen, Yue-e Chen, Xiaochu Zhang, Xiaochu Zhang, Xiaochu Zhang, Xiaochu Zhang, Xiaochu Zhang   +12 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Meta Inverse Reinforcement Learning via Maximum Reward Sharing for Human Motion Analysis [PDF]

, 2017
This work handles the inverse reinforcement learning (IRL) problem where only a small number of demonstrations are available from a demonstrator for each high-dimensional task, insufficient to estimate an accurate reward function.
Burdick, Joel W., Li, Kun
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Exploring governance challenges in South African public organisations

Cogent Social Sciences
Despite the incessant poor service delivery serving as a reminder to the existence of governance challenges, the existing literature gives scant attention to what constitute governance challenges in public organisations.
Ndimphiwe Mlamli Marawu, Reward Utete
doaj   +1 more source

Structural Reform in New Zealand: A Review [PDF]

This paper discusses the reasons for the change in economic policy direction adopted in New Zealand in 1984. The paper briefly outlines the economic history of New Zealand in the period from the early 1970's to 1996.
Reward, Peter
core  

Mega-Reward: Achieving Human-Level Play without Extrinsic Rewards

, 2019
Intrinsic rewards were introduced to simulate how human intelligence works; they are usually evaluated by intrinsically-motivated play, i.e., playing games without extrinsic rewards but evaluated with extrinsic rewards.
Lukasiewicz, Thomas, Song, Yuhang, Wang, Jianyi, Wojcicki, Andrzej, Xu, Mai, Xu, Zhenghua, Zhang, Shangtong   +6 more
core   +1 more source

Driving with Style: Inverse Reinforcement Learning in General-Purpose Planning for Automated Driving

, 2020
Behavior and motion planning play an important role in automated driving. Traditionally, behavior planners instruct local motion planners with predefined behaviors.
Großjohann, Simon, Homoceanu, Silviu, James, Vinit, Rosbach, Sascha, Roth, Stefan   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source