Results 91 to 100 of about 438,911 (302)

Primate amygdala neurons evaluate the progress of self-defined economic choice sequences

open access: yeseLife, 2016
The amygdala is a prime valuation structure yet its functions in advanced behaviors are poorly understood. We tested whether individual amygdala neurons encode a critical requirement for goal-directed behavior: the evaluation of progress during ...
Fabian Grabenhorst   +2 more
doaj   +1 more source

Dopamine promotes instrumental motivation, but reduces reward-related vigour

open access: yeseLife, 2020
We can be motivated when reward depends on performance, or merely by the prospect of a guaranteed reward. Performance-dependent (contingent) reward is instrumental, relying on an internal action-outcome model, whereas motivation by guaranteed reward may ...
John P Grogan   +3 more
doaj   +1 more source

REWARD-COST ORIENTATION: CONSTRUCT VALIDATION AND ITS IMPLICATIONS FOR DECISIONS UNDER RISK.

open access: yes, 1982
REWARD-COST ORIENTATION: CONSTRUCT VALIDATION AND ITS IMPLICATIONS FOR DECISIONS UNDER ...
GARY JOSEPH. LAUTENSCHLAGER (7985582)
core   +6 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The relationship between pay-for-performance and turnover intention

open access: yesSA Journal of Human Resource Management
Orientation: The current business environment is highly competitive, and organisations use reward strategy as a strategic tool to motivate employees to remain in the organisation and exceed set performance standards. Therefore, keeping them would require
Pitso Mohapi   +2 more
doaj   +1 more source

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

open access: yeseLife, 2017
Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice.
William Menegas   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The Rewards of Volunteering

open access: yesHealthcare Policy | Politiques de Santé, 2013
Whichever perspective you take on the “if a tree falls in the forest” question, it is certainly true that the easier a journal is to search and access, the more its content is likely to influence thinking, research and policy. With this in mind, I am happy to announce that the National Library of Medicine (NLM) recently decided to index Healthcare ...
openaire   +3 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Neural Correlates of Rewarded Response Inhibition in Youth at Risk for Problematic Alcohol Use

open access: yesFrontiers in Behavioral Neuroscience, 2017
Risk for substance use disorder (SUD) is associated with poor response inhibition and heightened reward sensitivity. During adolescence, incentives improve performance on response inhibition tasks and increase recruitment of cortical control areas (Geier
Brenden Tervo-Clemmens   +9 more
doaj   +1 more source

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