Results 81 to 90 of about 882,610 (273)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Exploring employees’ experiences with the performance appraisals at the South African Air Force

open access: yesSA Journal of Human Resource Management
Orientation: Performance management systems (PMS) are implemented through performance appraisals (PA), and during the PAs, fairness and justice should prevail to enhance employees’ positive experiences and satisfaction with the system. Research purpose: 
Bernardt Oschman, Mokgata A. Matjie
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Good science depends on good peer review

open access: yesIdeas in Ecology and Evolution, 2015
I argue that the quality of both scientific research and how it is communicated is maintained and improved through a process analogous to Darwinian evolution.
Michael E. Hochberg
doaj  

The Impact of the Cross-Cultural Factors on Getting the Management Performances within AKER Multinational Company [PDF]

open access: yesRevista de Management Comparat International, 2009
Our paper approaches the aspects connected to the analysis of the values system specific to the AKER multinational group, world leader on the market targets represented by cruises and ferryboats, commercial ships and offshore platforms.
Adriana OLARU, Alexandru CAPATINA
doaj  

Bad News: An Experimental Study on the Informational Effects of Rewards [PDF]

open access: yes
Both psychologists and economists have argued that rewards often have hidden costs. One possible reason is that the principal may have incentives to offer higher rewards when she knows the task to be dificult.
Andrei Bremzeny   +3 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Total rewards for attracting and retaining Millennials in the workplace post-COVID-19

open access: yesSA Journal of Human Resource Management
Orientation: Millennials (born 1981–2000) are set to shape South Africa’s banking sector post-coronavirus disease 2019 (COVID-19). However, their unique work expectations pose challenges for attraction and retention.
Calvin M. Mabaso, Shane Mathebula
doaj   +1 more source

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