Results 231 to 240 of about 231,693 (293)

Subregion‐specific perineuronal net remodelling in the dorsal hippocampus drives vulnerability and resilience to chronic stress: The role of venlafaxine treatment

British Journal of Pharmacology, Volume 183, Issue 21, Page 6291-6305, November 2026.
Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio, Arianna Palumbo, Maria Teresa Gallo, Filippo Umberto Tancredi Veronesi, Giorgia Cortinovis, Piotr Gruca, Magdalena Lason, Ewa Litwa, Dominika Biala, Fabio Fumagalli, Mariusz Papp, Francesca Calabrese   +11 more
wiley   +1 more source

Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state. [PDF]

Mol Cell
Kainth AS, Sirjoosingh P, Werner MS, Gupta A, Koide A, Koide S, Ruthenburg AJ.   +6 more
europepmc   +1 more source

High‐variance phenome database reveals important roles of WD40 proteins in the plant pathogenic fungus Fusarium graminearum

New Phytologist, Volume 252, Issue 3, Page 1215-1231, November 2026.
Functional analysis of predicted interaction‐associated WD40 blades in Fgwd101 and Fgwd048 of Fusarium graminearum. Summary WD40 is a highly conserved protein domain in eukaryotes that functions as a versatile platform for protein–protein interactions and participates in diverse biological processes.
Soyoung Choi, Nahyun Lee, Jiyeun Park, Hosung Jeon, Sieun Kim, Jung‐Eun Kim, Jiyoung Shin, Heeji Moon, Kyunghun Min, Yejin Choi, Aram Hwangbo, Hun Kim, Gyung Ja Choi, Yin‐Won Lee, Dae‐Geun Song, Hokyoung Son   +15 more
wiley   +1 more source

Genetic Mapping and Diversity of Indigenous and Exotic Rabbits: Adaptive and Conservation Strategies. [PDF]

Genes (Basel)
Ahmed MM, Abousaad SM, Abdel-Magid SS, El-Tantawi SM, Ali HM, El-Gendy EA, Abouzeid NA, Yang L, Hayes K, Hamilton MS, Abouzeid AM, Wang Y.   +11 more
europepmc   +1 more source

Functional Heterogeneity of the Autism Spectrum Disorder‐Associated Gut Microbial Ecosystem Revealed by Fecal Lipopolysaccharides and Bacterial Proteomic Profiling

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
Gut microbiota associated with pediatric autism spectrum disorder exhibit functional heterogeneity characterized by altered fecal lipopolysaccharide landscapes, metabolic remodeling, and enhanced microglial inflammatory responses despite largely preserved microbial composition.
Stefania De Chiara, Angela Di Somma, Valentina Mazziotti, Serena Coppola, Franca Oglio, Lidia Tammaro, Maria Pia Riccio, Carmela Bravaccio, Antonio Molinaro, Roberto Berni Canani, Flaviana Di Lorenzo   +10 more
wiley   +1 more source

NCBP1 stress signaling drives alternative S6K1 splicing inhibiting translation. [PDF]

Nat Chem Biol
Chang D, Assari M, Suwathep C, Sappakhaw K, Uttamapinant C, Long MJC, Aye Y.   +6 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, Volume 600, Issue 20, Page 3106-3129, October 2026.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Fibro‐Adipogenic Progenitors From Skeletal Muscle Enhance Microvascular Angiogenesis in a 3D Model

Advanced Biology, Volume 10, Issue 10, October 2026.
Fibro‐adipogenic progenitors (FAPs) are skeletal muscle stem cells that reside between fibers and near capillaries. However, relatively few studies have investigated interactions between FAPs and the microvasculature. We demonstrate that FAPs enhance angiogenesis of microvascular fragments (MVFs) by promoting increases in vessel percentage area and ...
Christian M. Mendiondo, Andrew R. King, Felipe Morales, David Leyton‐Cifuentes, Theodore J. Pabst, Eric M. Brey, Christopher R. Rathbone   +6 more
wiley   +1 more source

ADAR1 and ADAR2 associate with the RNA exosome and modulate RNA stability. [PDF]

Nucleic Acids Res
Vukić D, Du Q, Cherian A, Amoruso D, Brožinová K, Wacheul L, Lacovich V, Zorbas C, Yadav L, Sedmík J, Keskitalo S, Hajji K, Stejskal S, Varjosalo M, Lafontaine DLJ, Keegan LP, O'Connell MA.   +16 more
europepmc   +1 more source

S‐Nitrosothiols as Thiol‐Protecting Groups for Controlled Thiol‐Maleimide Crosslinking of Homogeneous Soft Hydrogels

Advanced Materials, Volume 38, Issue 57, 13 October 2026.
Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna, Michelle J. Iwohn, Maximilian Seifermann, Stefan Heißler, Maike Schliephake, Franziska Dopp, Claudia Muhle‐Goll, Pavel A. Levkin   +7 more
wiley   +1 more source