Abstract Purpose To compare the effects of monotherapy with intravitreal ranibizumab, aflibercept and bevacizumab on retinal ganglion cell layer (RGCL) and retinal nerve fibre layer (RNFL) in patients with naïve neovascular age‐related macular degeneration (nAMD). Methods This is a retrospective cohort study with three‐groups comparison.
Yaser Abu Dail +3 more
wiley +3 more sources
Structural impairment patterns in peripapillary retinal fiber layer and retinal ganglion cell layer in mitochondrial optic neuropathies [PDF]
AIM: To evaluate the structural injure patterns in peripapillary retinal fiber layer (pRNFL), retinal ganglion cell layer (RGCL) and their correlations to visual function in various mitochondrial optic neuropathies (MON) to offer help to their ...
Da Teng +8 more
doaj +3 more sources
Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation [PDF]
Abstract A variety of diseases lead to degeneration of retinal ganglion cells (RGCs) and their axons within the optic nerve resulting in loss of visual function. Although current therapies may delay RGC loss, they do not restore visual function or completely halt disease progression.
Alessia Tassoni +4 more
wiley +2 more sources
Inner retinal layer change in glaucoma patients receiving anti-VEGF for neovascular age related macular degeneration. [PDF]
PURPOSE The purpose was to evaluate the effects of long-term anti-VEGF treatment on the retinal nerve fiber layer (RNFL) and retinal ganglion cell layer (RGCL) thickness for patients with neovascular AMD and glaucoma.
Karpe, Aashraya +3 more
core +4 more sources
Choroidal Thickness in Patients with Mild Cognitive Impairment and Alzheimer’s Type Dementia [PDF]
Aim. To asses both choroidal thickness differences among Alzheimer’s type dementia (ATD) patients, mild cognitive impairment (MCI) patients, and healthy control (C) subjects and choroidal thickness relationships with cognitive performance. Methods. A total of 246 eyes of 123 people (41 ATD, 38 MCI, and 44 healthy C subjects) were included in this study.
Mehmet Bulut +8 more
wiley +5 more sources
Mean Retinal Ganglion Cell Layer Thickness in Healthy Adults Measured by OCT at a Tertiary Care Hospital in Karachi, Pakistan [PDF]
Objective: To determine normative values of retinal ganglion cell layer (RGCL) thickness in healthy Pakistani adults using Heidelberg Spectralis optical coherence tomography (OCT) and evaluate its correlation with age, gender, axial length, and ...
Munaza Munir +4 more
doaj +6 more sources
Retinal and Choroidal Effects of Continuous Positive Airway Pressure as Treatment for Sleep Apnea: Results at 12 Months. [PDF]
Background: To determine the impacts of continuous positive airway pressure (CPAP) treatment on retinal and choroidal thickness measurement in individuals with obstructive sleep apnea (OSA).
Naranjo-Bonilla P +3 more
europepmc +4 more sources
Altered spatial summation optimizes visual function in axial myopia. [PDF]
This study demonstrates significant differences between the area of complete spatial summation (Ricco’s area, RA) in eyes with and without non-pathological, axial myopia.
Stapley V +3 more
europepmc +3 more sources
Perimetric Stimuli Undergoing Complete Spatial Summation Optimize the Detection of Retinal Ganglion Cell Density Gradients in Healthy Observers. [PDF]
Purpose: To compare the ability of conventional luminance-modulating perimetric stimuli and an area-modulation stimulus (AMS) designed to measure changes in complete spatial summation to identify physiological retinal ganglion cell density (RGCD ...
Campbell CS +5 more
europepmc +3 more sources
Impact of intravitreal ranibizumab, aflibercept and bevacizumab on retinal ganglion cell and nerve fibre layer thickness in Neovascular age-related macular degeneration [PDF]
Purpose: To compare the effects of monotherapy with intravitreal ranibizumab, aflibercept and bevacizumab on retinal ganglion cell layer (RGCL) and retinal nerve fibre layer (RNFL) in patients with naïve neovascular age-related macular degeneration ...
Abdin, Alaa D. +3 more
core +1 more source

