The retinal ganglion cell layer reflects neurodegenerative changes in cognitively unimpaired individuals. [PDF]
AbstractBackgroundTo evaluate a wide range of optical coherence tomography (OCT) parameters for possible application as a screening tool for cognitively healthy individuals at risk of Alzheimer’s disease (AD), assessing the potential relationship with established cerebrospinal fluid (CSF) core AD biomarkers and magnetic resonance imaging (MRI ...
López-de-Eguileta A +16 more
europepmc +6 more sources
Assessment of the Retinal Ganglion Cell Layer after Uncomplicated Cataract Surgery [PDF]
(1) Background: This research aimed to evaluate the changes in ganglion cell layer thickness (GCLT) after uncomplicated cataract surgery in patients without previous ocular pathology and the impact of the appearance of cystoid macular edema on the GCLT and visual acuity.
Abou-Jokh Rajab B +3 more
europepmc +4 more sources
Structural impairment patterns in peripapillary retinal fiber layer and retinal ganglion cell layer in mitochondrial optic neuropathies. [PDF]
To evaluate the structural injure patterns in peripapillary retinal fiber layer (pRNFL), retinal ganglion cell layer (RGCL) and their correlations to visual function in various mitochondrial optic neuropathies (MON) to offer help to their differential diagnosis.Totally 32 MON patients (60 eyes) were recruited within 6mo after clinical onsets, including
Teng D +8 more
europepmc +4 more sources
Baseline histological and morphometric description of the retina in the Pied Crow (Corvus albus) [PDF]
Objective The Pied Crow (Corvus albus) is a visually guided diurnal corvid widely distributed across sub-Saharan Africa, yet detailed descriptions of its ocular microanatomy remain limited.
Olanrewaju I. Fatola +3 more
doaj +2 more sources
Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]
Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
A Lux +68 more
core +17 more sources
HYPERREFLECTIVE BAND IN THE GANGLION CELL LAYER IN RETINITIS PIGMENTOSA
Purpose: To describe a sign that takes the form of a continuous hyperreflective band within the thickness of the ganglion cell layer (GCL), thus dubbed the “hyperreflective ganglion cell layer band” (HGB), which the authors detected in a fraction of patients affected by retinitis pigmentosa (RP).
Alessio, Antropoli +9 more
openaire +2 more sources
Although mutations in ADAMTS10 have long been known to cause autosomal recessive Weill-Marchesani Syndrome which is characterized by short stature and ocular abnormalities, more recent work has shown that certain mutations in ADAMTS10 cause glaucoma in ...
Lauren K. Wareham +8 more
doaj +1 more source
Objective: To assess the alterations of individual retinal layer thickness at different stages of diabetic retinopathy (DR) and its role in determining DR severity.
Zulvikar Syambani Ulhaq +6 more
doaj +1 more source
Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation. [PDF]
Alzheimer's disease (AD) is an age-related condition characterized by accumulation of neurotoxic amyloid β peptides (Aβ) in brain and retina. Because bone marrow transplantation (BMT) results in decreased cerebral Aβ in experimental AD, we hypothesized ...
Yue Yang +6 more
doaj +1 more source
Relationship between Visual Dysfunction and Retinal Changes in Patients with Multiple Sclerosis. [PDF]
To evaluate structural changes in the retina and their correlation with visual dysfunction in patients with multiple sclerosis.Patients with multiple sclerosis (n = 84) and healthy controls (n = 84) underwent structural evaluation of the retinal nerve ...
Maria Satue +10 more
doaj +1 more source

