Results 41 to 50 of about 68,022 (253)

Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids [PDF]

, 2019
Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for directing stem cell renewal and differentiation.
Al-Aama, Jumana, Asfour, Hani Z., Ding, Yuchun, Doherty, Mary, Dorgau, Birthe, Felemban, Majed, Hallam, Dean, Hilgen, Gerrit, Hunt, Nicola Claire, Kiening, Martin, Krasnogor, Natalio, Lako, Majlinda, Sernagor, Evelyne, White, Kathryn, Whitfield, Phil, Zerti, Darin   +15 more
core   +2 more sources

Effect of protein complex Nogo66-FA on retinal microenvironment in rats with chronic intraocular hypertension

Di-san junyi daxue xuebao, 2021
Objective To investigate the effect of protein complex, Nogo66 and Freund's adjuvant (FA), on retinal microenvironment in rats with chronic ocular hypertension. Methods After the rat model of chronic high intraocular pressure was established on the right
CHENG Ming, HE Xiangge
doaj   +1 more source

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer reviewedPublisher ...
Adams JC, Agathocleous M, Aihara K, Amy S. Findlay, Austin CP, Cayouette M, Cepko CL, Chizu Nakamoto, de Iongh R, Ehrlich D, Elaine Durward, Ewa D. Zakrzewska, Fekete DM, Flanagan JG, Frade JM, Galvez JM, Hansen MJ, Harada H, Harpavat S, Hashimoto T, Holt CE, Hu WY, Isenmann S, Jablonski MM, Jablonski MM, Jiang Y, Jiang Y, Katahira T, Koga A, Kuroda S, Layer PG, Marianne Bronner, Martinez-Morales JR, Masai I, Masaru Nakamoto, Matsuhashi S, Matsuhashi S, Matsuoka H, Matsuyama S, Matsuyama S, McCabe KL, McCabe KL, McLaughlin T, Moore SW, Munemasa Y, Nakamura R, Nelson BR, Nelson BR, Oyasu M, Patel A, Prada C, Price J, Rachel RA, Raymond SM, Sato Y, Snow RL, Soh-Leh Kuan, Stiemke MM, Strauss O, Takuma Endo, Wang JT, Watanabe TK, Wetts R, Xiang M, Yee JK, Zhang XM, Zhang XM, Zhufeng Ouyang   +67 more
core   +1 more source

Cirrhosis-induced morphological changes in the retina:possible role of endogenous opioid [PDF]

International Journal of Ophthalmology, 2015
AIM:To investigate the impact of cirrhosis on retinal morphology and to evaluate the role of endogenous opioids as a mediator in cirrhosis induced retinal change.METHODS:Thirty-six male rats were divided into 3 main groups; the common bile duct ligated ...
Mohammad Abdullah Algazo, Saeed Amiri-ghashlaghi, Bahram Delfan, Gholamreza Hassanzadeh, Fatemeh Sabbagh-ziarani, Farahnaz Jazaeri, Ahmad Reza Dehpour   +6 more
doaj   +1 more source

Age-Dependent Susceptibility of the Retinal Ganglion Cell Layer to Cell Death

Investigative Opthalmology & Visual Science, 2006
The purpose of this study was to determine the susceptibility of the retinal ganglion cell layer (GCL) to apoptosis after optic nerve transection and excitotoxic stimulus and to investigate the regulation of apoptosis in the GCL during development.
Declan P, McKernan, Ciara, Caplis, Maryanne, Donovan, Colm J, O'brien, Thomas G, Cotter   +4 more
openaire   +2 more sources

Retinal nerve fibre layer, ganglion cell layer and choroid thinning in migraine with aura [PDF]

BMC Ophthalmology, 2014
The aim of this study was to investigate the thickness of the retinal nerve fiber layer (RNFL), the ganglion cell layer (GCL), and choroid thickness (CT) in patients who have migraines, with and without aura, using spectral optical coherence tomography (OCT).Forty-five patients who had migraines without aura (Group 1), 45 patients who had migraines ...
Tanyildiz, Burak, Ekinci, Metin, Ceylan, Erdinc, Cagatay, Halil Huseyin, HÜSEYİNOĞLU, NERGİZ, Cakici, Ozgur, Kartal, Baki, KELEŞ, Sadullah   +7 more
openaire   +4 more sources

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick, Ngolab, Jennifer, Rissman, Robert A   +2 more
core   +1 more source

Analysis of inner and outer retinal layers using spectral domain optical coherence tomography automated segmentation software in ocular hypertensive and glaucoma patients. [PDF]

PLoS ONE, 2018
To analyse the morphological features and diagnostic ability of eight macular retinal layers using a new segmentation software Heidelberg's Spectralis Optical Coherence Tomography (SD-OCT) in healthy, ocular hypertensive and primary open angle glaucoma ...
Pilar Cifuentes-Canorea, Jorge Ruiz-Medrano, Rosa Gutierrez-Bonet, Pablo Peña-Garcia, Federico Saenz-Frances, Julian Garcia-Feijoo, Jose Maria Martinez-de-la-Casa   +6 more
doaj   +1 more source

Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation. [PDF]

, 1991
The integrin alpha 6 beta 1 is a prominent laminin receptor used by many cell types. In the present work, we isolate clones and determine the primary sequence of the chick integrin alpha 6 subunit.
de Curtis, I, Quaranta, V, Reichardt, LF, Tamura, RN   +3 more
core   +3 more sources

Retinal nerve fiber layer, ganglion cell complex, and choroidal thicknesses in migraine [PDF]

Arquivos Brasileiros de Oftalmologia, 2016
To evaluate the thicknesses of the peripapillary retinal nerve fiber layer (RNFL), ganglion cell complex (GCL), and choroid layer using spectral domain optical coherence tomography (SD-OCT) for investigating the effects of vascular changes on the eye and optic nerve in patients who have migraine with aura.Forty-five patients who had migraine with aura (
Uzun, Salih, Pehlivan, Emre
openaire   +8 more sources