Results 51 to 60 of about 68,022 (253)

An in vivo evaluation of Brilliant Blue G in animals and humans [PDF]

, 2008
Background/Aims: To evaluate the retinal toxicity of Brilliant Blue G (BBG) following intravitreal injection in rat eyes and examine the biocompatibility and the staining properties in humans.Methods: BBG was injected into the 11 rat eyes to evaluate ...
Fiedorowicz, M., Grüterich, Martin, Haritoglou, Christos, Kampik, Anselm, May, C. A., Nentwich, Martin M., Priglinger, Siegfried G., Remy, M., Schuettauf, F., Schumann, Ricarda G., Thaler, S.   +10 more
core   +1 more source

Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury

Cell & Bioscience, 2022
Background Despite current intervention measures/therapies are able to ameliorate neuronal death following retinal injuries/diseases, the recovery of visual function remains unsatisfactory.
Tu Hu, Shuhan Meng, Qianyue Zhang, Shuang Song, Cheng Tan, Jufang Huang, Dan Chen   +6 more
doaj   +1 more source

Relationship between optical coherence tomography and electrophysiology of the visual pathway in non-optic neuritis eyes of multiple sclerosis patients. [PDF]

PLoS ONE, 2014
PURPOSE: Loss of retinal ganglion cells in in non-optic neuritis eyes of Multiple Sclerosis patients (MS-NON) has recently been demonstrated. However, the pathological basis of this loss at present is not clear.
Prema Sriram, Chenyu Wang, Con Yiannikas, Raymond Garrick, Michael Barnett, John Parratt, Stuart L Graham, Hemamalini Arvind, Alexander Klistorner   +8 more
doaj   +1 more source

Estimated Retinal Ganglion Cell Counts in Glaucomatous Eyes with Localized Retinal Nerve Fiber Layer Defects [PDF]

American Journal of Ophthalmology, 2013
To estimate retinal ganglion cell (RGC) losses associated with visible glaucomatous localized retinal nerve fiber layer (RNFL) defects.Observational cross-sectional study.A multicenter study of 198 normal eyes (138 subjects) and 66 glaucomatous eyes (55 subjects) recruited from the Diagnostic Innovations in Glaucoma Study and the African Descent and ...
Tatham, Andrew J, Weinreb, Robert N, Zangwill, Linda M, Liebmann, Jeffrey M, Girkin, Christopher A, Medeiros, Felipe A   +5 more
openaire   +4 more sources

Novel rodent models for macular research [PDF]

, 2010
Background: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Huber, Gesine, Heynen, Severin, Imsand, Coni, vom Hagen, Franziska, Muehlfriedel, Regine, Tanimoto, Naoyuki, Feng, Yuxi, Hammes, Hans-Peter, Grimm, Christian, Peichl, Leo, Seeliger, Mathias W., Beck, Susanne Christiane   +11 more
core   +1 more source

Changes in retinal nerve fiber layer, ganglion cell complex, and ganglion cell layer thickness in thyroid eye disease: A systematic review

Taiwan Journal of Ophthalmology, 2023
Abstract Thyroid eye disease (TED) is characterized by progressive orbital inflammation. In severe cases, it can lead to dysthyroid optic neuropathy (DON), involving death of retinal ganglion cells and permanent vision loss. Imaging with optical coherence tomography (OCT) has enabled noninvasive examination of the structural impact of the ...
Lillian Chien, Cammille C. Go, Gabriela M. Lahaie Luna, César A. Briceño   +3 more
openaire   +3 more sources

Relationship between Retinal Inner Nuclear Layer Thickness and Severity of Visual Field Loss in Glaucoma

Scientific Reports, 2017
Glaucoma is a disease characterized by pathologic changes in inner retinal layers, which are comprised of retinal ganglion cells (RGCs). As retinal ganglion cells (RGCs) cross over other retinal neurons that are connected by synapses, it is meaningful to
Eun Kyoung Kim, Hae-Young Lopilly Park, Chan Kee Park   +2 more
doaj   +1 more source

The effect of off-pump coronary bypass graft surgery on subfoveal choroidal thickness, ganglion cell complex, and retinal nerve fiber layer thickness

Therapeutic Advances in Ophthalmology, 2023
Background: Cardiac surgery has been associated with adverse ocular events. Off-pump coronary artery bypass graft surgery evades the systemic inflammatory response seen in extracorporeal circulation and is superior to on-pump surgery with regard to end ...
Nesime Setge Tıskaoğlu, Alper Yazıcı, Abdulkadir Ercan, Kübra Tınç   +3 more
doaj   +1 more source

Retinal Ganglion Cell Layer Thickness and Local Visual Field Sensitivity in Glaucoma [PDF]

Archives of Ophthalmology, 2011
To compare loss in sensitivity measured using standard automated perimetry (SAP) with local retinal ganglion cell layer (RGC) thickness measured using frequency-domain optical coherence tomography in the macula of patients with glaucoma.To compare corresponding locations of RGC thickness with total deviation (TD) of 10-2 SAP for 14 patients with ...
Ali S, Raza, Jungsuk, Cho, Carlos G V, de Moraes, Min, Wang, Xian, Zhang, Randy H, Kardon, Jeffrey M, Liebmann, Robert, Ritch, Donald C, Hood   +8 more
openaire   +2 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source