Neuronal Nitric Oxide Synthase Is Crucial for Ganglion Cell Death in Rat Retinal Explant Cultures
Journal of Pharmacological Sciences, 2004 We examined possible involvement of nitric oxide synthase (NOS) on ganglion cell death in explant cultures of neonatal rat retina. Survival of retinal ganglion cells was significantly prolonged by a broad-spectrum NOS inhibitor Nω-nitro-L-arginine ...
Hiroshi Katsuki +4 more
doaj +1 more source
Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells. [PDF]
, 2018 The production of vertebrate retinal projection neurons, retinal ganglion cells (RGCs), is regulated by cell-intrinsic determinants and cell-to-cell signaling events.
Hashimoto, Takao +3 more
core +1 more source
Deciphering perivascular macrophages and microglia in the retinal ganglion cell layers
Frontiers in Cell and Developmental Biology, 2023 Introduction: The classically defined two retinal microglia layers are distributed in inner and outer plexiform layers. Although there are some reports that retinal microglia are also superficially located around the ganglion cell layer (GCL) in contact with the vitreous, there has been a lack of detailed descriptions and not fully understood yet ...
Jehwi Jeon +11 more
openaire +3 more sources
Hyperactivity of ON-type retinal ganglion cells in streptozotocin-induced diabetic mice. [PDF]
PLoS ONE, 2013 Impairment of visual function has been detected in the early stage of diabetes but the underlying neural mechanisms involved are largely unknown.
Jun Yu +5 more
doaj +1 more source
General features of the retinal connectome determine the computation of motion anticipation [PDF]
, 2015 Motion anticipation allows the visual system to compensate for the slow speed of phototransduction so that a moving object can be accurately located.
Asari +81 more
core +2 more sources
Optical coherence tomography angiography in eyes with good visual acuity recovery after treatment for optic neuritis. [PDF]
PLoS ONE, 2017 To evaluate the retinal perfusion using optical coherence tomography (OCT) angiography in eyes with good visual acuity recovery after treatment for optic neuritis (ON).Seven eyes of seven patients with good visual acuity recovery after treatment for ...
Tomoaki Higashiyama +2 more
doaj +1 more source
RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells. [PDF]
, 2015 A subset of retinal ganglion cells is intrinsically photosensitive (ipRGCs) and contributes directly to the pupillary light reflex and circadian photoentrainment under bright-light conditions.
Berson, David M +8 more
core +2 more sources
Transient requirement for ganglion cells during assembly of retinal synaptic layers [PDF]
Development, 2004 The inner plexiform layer (IPL) of the vertebrate retina comprises functionally specialized sublaminae, representing connections between bipolar,amacrine and ganglion cells with distinct visual functions. Developmental mechanisms that target neurites to the correct synaptic sublaminae are largely unknown.
Kay, J N +6 more
openaire +4 more sources
Journal of Ophthalmology, 2015 Purpose. To assess the repeatability of spectral-domain optical coherence tomography to measure macular and perimacular ganglion cell complex thicknesses and compare retinal ganglion cell parameters between algorithms. Methods. Ninety-two nonglaucomatous
Dorothy S. K. Ng +6 more
doaj +1 more source
Minimizing activation of overlying axons with epiretinal stimulation: The role of fiber orientation and electrode configuration. [PDF]
PLoS ONE, 2018 Currently, a challenge in electrical stimulation of the retina with a visual prosthesis (bionic eye) is to excite only the cells lying directly under the electrode in the ganglion cell layer, while avoiding excitation of axon bundles that pass over the ...
Timothy B Esler +5 more
doaj +1 more source