Results 151 to 160 of about 118,582 (236)

In Vivo Evaluation of Preconditioned Adipose‐Derived Stromal Cells Reveals Limited Impact on Vascular and ECM Remodeling in Polymer Scaffolds

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 5, May 2026.
ABSTRACT Polymer scaffolds are a promising platform for the transplantation of insulin‐producing cells in Type 1 Diabetes. While vascularization has been a primary focus due to its role in oxygen and nutrient delivery, the interplay between blood vessels and the extracellular matrix (ECM) is increasingly recognized as critical for establishing a stable
Erika Pinheiro‐Machado   +5 more
wiley   +1 more source

RVG‐Modified BMSCs‐Derived Small Extracellular Vesicles Loaded With miR‐21 Alleviate Neuronal Injury Resulted From Excessive Autophagy via Targeting PTEN/Akt/mTOR Pathway After Cerebral Ischaemia

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
Bioengineered brain targeting RVG‐modified BMSCs‐derived small extracellular vesicles loaded with miR‐21 alleviate excessive autophagic neuronal injury after cerebral ischaemia via PTEN/Akt/mTOR pathway. ABSTRACT Ischaemic stroke (IS) leads to tragic disability and high adult mortality, while there are limited therapeutic measures for it.
Yiyang Li   +9 more
wiley   +1 more source

Aminoacyl‐tRNA Synthetases: Variant Classification, Functional Assays, and Emerging Therapeutic Strategies

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (aaRS) are essential enzymes that charge tRNAs with their corresponding amino acids, playing a critical role in protein synthesis. All 37 nuclear‐encoded ARS genes, comprising both cytosolic (ARS1) and mitochondrial (ARS2) isoforms, have now been linked to human disease.
M. I. Mendes   +17 more
wiley   +1 more source

Limits of Transfusion Burden as a Predictor of Mortality in Severely Injured Trauma Patients. [PDF]

open access: yesOpen Access Emerg Med
Barouqa M   +5 more
europepmc   +1 more source

Cerebral Hemodynamic Changes During Cardiac Surgery: A Feasibility MR Study in Piglets

open access: yesNMR in Biomedicine, Volume 39, Issue 5, May 2026.
Congenital heart disease surgery in infants requires cardiopulmonary bypass (CPB), which increases the risk of brain injury. Conventional heart‐lung machines (HLMs) cannot operate inside MRI scanners, limiting real‐time assessment of cerebral changes. We developed an MR‐conditional HLM and tested it in piglets during CPB.
Dominik T. Schulte   +13 more
wiley   +1 more source

Hybrid Modification Strategies of Metal–Organic Frameworks: A Review on Structural Design and Environmental Applications

open access: yesChemistryOpen, Volume 15, Issue 5, May 2026.
This review examines how hybrid modification strategies enhance the structural design and environmental performance of metal–organic frameworks (MOFs). It outlines key synthesis routes, functionalization approaches, and integration with complementary materials, highlighting advances in pollutant removal, sensing, and sustainable remediation.
Samar H. Elagamy   +3 more
wiley   +1 more source

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