Results 161 to 170 of about 118,582 (236)

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Characterisation of RHD and RHCE variations in blood donors from Jazan Province, Southwestern Saudi Arabia. [PDF]

Transfus Med
Madkhali MM, Khormy M, Meshi AA, Kameli B, Ghazwani K, Sufyani O, Hakami S, Khawaji Y, Mobarki AA, Essawi K, Hakami W, Alyahyawi Y, Madkhali AM, Dobie G, Hamali HA.   +14 more
europepmc   +1 more source

Midazolam Dosing During CRRT: A Combined Ex Vivo and Physiologically‐Based Pharmacokinetic Approach

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Children supported with continuous renal replacement therapy have high mortality rates ranging from 30% to 70%. The cause of this high mortality is multifactorial and includes ineffective drug dosing and altered drug pharmacokinetics. Changes in drug exposure can result from (1) underlying disease; and (2) direct drug interaction and/or ...
Autumn M. McKnite, Abdullah Hamadeh, J. Porter Hunt, Danielle J. Green, Carina Imburgia, Aviva Whelan, Rachel Hudson, Andrew Chevalier, Cheryl L. Mathis, Michelle J. Yang, Jamie P. Dwyer, Andrea Edginton, Kevin M. Watt   +12 more
wiley   +1 more source

Impact of Sleep Apnea Treatment With Continuous Positive Airway Pressure (CPAP) on Blood Pressure Control in Resistant Hypertension: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Sabry M, Gundala C, Hamad M, Tummala N, Hamid AA, Mohamed AE, Zia U, Hassan AM, Essani B, Abid M, Karimi B.   +10 more
europepmc   +1 more source

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

Small, Volume 22, Issue 26, 8 May 2026.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk, Rima Nuwayhid, Stefaniya Gaydarova, Eva Bittrich, Natalia Makarova, Susanne Boye, Christo Tzachev, Jan C. Simon, Sandra Franz, Albena Lederer   +9 more
wiley   +1 more source

Clonal hematopoiesis driven by Dnmt3a mutations promotes metabolic disease development in mice. [PDF]

J Clin Invest
Yan B, Yuan Q, Buttigieg MM, Kaur P, McKee AR, Shabashvili DE, Vlasschaert C, Bick AG, Rauh MJ, Guryanova OA.   +9 more
europepmc   +1 more source

The Problem of Hemolytic Disease of the Newborn and its Management in a General Hospital [PDF]

, 1958
Sacks, Martin O.
core   +1 more source

Extracts From Grapefruit (Citrus paradisi) Peel via Microwave‐Assisted and Conventional Extractions: Evaluation of Nosema Infection and Toxicity in Honey Bees

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Conventional and microwave‐assisted extractions of grapefruit peels were optimized using response surface methodology (RSM) based on TPC, TFC, and antioxidant activity (DPPH). The phytochemical profiles of the two optimum extracts were characterized via HPLC before evaluating their acute and chronic toxicity, as well as their effects on honey bee (Apis
Muhammet Mükerrem Kaya, Hidayet Tutun, Nilüfer Vural, Özlem Özmen, Samet Okuyan   +4 more
wiley   +1 more source

Accelerated enhanced recovery after colorectal surgery with early discharge: A systematic review and meta-analysis. [PDF]

Langenbecks Arch Surg
Yu ZH, Wang LM, Chan LY, You JF, Lin GP.
europepmc   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source