Results 181 to 190 of about 29,693 (245)

Prediction of cognitive outcome and progression to dementia using ω6‐PUFA/ω3‐PUFA ratio

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION The polyunsaturated fatty acids (PUFAs) omega‐6 (ω6) and omega‐3 (ω3) are linked to cognitive performance and Alzheimer's‐type dementia (DAT), but ω3‐PUFA supplementation offers limited benefits. We propose that the ω6‐PUFA/ω3‐PUFA ratio better explains cognitive decline and DAT risk.
Víctor Andrade, Luca Kleineidam, Holger Wagner‐Thelen, Tommaso Ballarini, Rafael Campos‐Martin, Pamela Martino‐Adami, Kumar Parijat Tripathi, Sophie Guyonnet, Bruno Vellas, Martin Scherer, Wolfgang Maier, Michael Pentzek, Matthias Schmid, Steffi Riedel‐Heller, Siegfried Weyerer, Horst Bickel, Birgitt Wiese, Sarah Egert, Michael Wagner, Alfredo Ramírez   +19 more
wiley   +1 more source

[Rh blood group: Review and importance of genotyping]. [PDF]

Rev Med Inst Mex Seguro Soc
Campos-Aguirre E, Mendoza-Rangel MF, Rodríguez-Silverio J, Benítez-Arvizu G.   +3 more
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1552-1566, June 2026.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Blood-based kinase activity profiling to predict response to immune checkpoint inhibitors in patients with advanced stage NSCLC: the prospective IOpener study. [PDF]

J Immunother Cancer
de Joode K, Groen HJ, Heuvel MVD, Kloover JS, Van Der Meer F, Van der Leest CH, Van Den Borne B, De Wijn R, Hurkmans DP, Van den Heuvel DMA, Pinedo HM, Kapiteijn E, Debets R, Verdegaal EME, Van der Burg SH, Groten JP, Aerts JGJV, Mathijssen RHJ.   +17 more
europepmc   +1 more source

Optimizing Outcomes in Elderly HNSCC: Efficacy of UFT Metronomic Therapy

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Introduction Head and neck squamous cell carcinoma (HNSCC) remains a significant clinical challenge, especially in elderly patients with advanced‐stage disease and multiple comorbidities. Metronomic chemotherapy with oral tegafur‐uracil (UFT) offers a low‐toxicity maintenance option that may improve outcomes.
Hsu‐Lin Lee, Po‐Huang Chen, Yu‐Guang Chen, Jia‐Hong Chen, Tzu‐Chuan Huang, Ching‐Liang Ho, Ren‐Hua Ye   +6 more
wiley   +1 more source

Reflex vasodilation and sweating in response to passive whole body heating are blunted in women with major depressive disorder. [PDF]

J Appl Physiol (1985)
Fisher KG, Leach OK, Greaney JL, Alexander LM, Kenney WL.   +4 more
europepmc   +1 more source

Clinical Diagnosis and Treatment of Ruptured Renal Artery Aneurysm During Pregnancy: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Rupture of renal artery aneurysm during pregnancy (PSRRAA) is a life‐threatening emergency that can lead to adverse outcomes for both the mother and the fetus. This paper reports a case of right renal artery aneurysm (RAA) rupture in a 32‐year‐old pregnant woman at 37 weeks of gestation, and discusses the clinical diagnosis and treatment of ...
SuFang Qiu, Yao Xiao, Yan Chen, Minglin Zhong   +3 more
wiley   +1 more source

RH gene inversion-recombination as a major mechanism of the D phenotype in China. [PDF]

Blood Transfus
Ying Y, Zhang J, Hong X, Yuan W, Zhang B, Huang X, Xu X, Zhu F.   +7 more
europepmc   +1 more source

Human brain pericytes protect the blood–brain barrier from triple‐negative breast cancer cells while promoting tumor aggressiveness

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract The majority of breast cancer‐related deaths result from metastatic progression, especially brain metastasis, associated with the poorest prognosis. Patients with triple‐negative breast cancer (TNBC) are particularly prone to developing brain metastases.
Eloise Happernegg, Marine Carroué, Julien Cicero, Lucie Dehouck, Fumitaka Shimizu, Takashi Kanda, Chann Lagadec, Fabien Gosselet, Xuefen Le Bourhis, Maxime Culot, Robert‐Alain Toillon, Caroline Mysiorek   +11 more
wiley   +1 more source

ABO blood group and Rhesus factor as potential markers in papillary thyroid cancer: a retrospective comparative analysis (2015-2023). [PDF]

Langenbecks Arch Surg
Aydoğdu YF, Büyükkasap Ç, Göbüt H, Akın M.   +3 more
europepmc   +1 more source