Results 51 to 60 of about 16,904 (234)

Bioimaging of sense organs and the central nervous system in extant fishes and reptiles in situ: A review

The Anatomical Record, EarlyView.
Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin, Kara E. Yopak, Jenna M. Crowe‐Riddell, Victoria Camilieri‐Asch, Caroline C. Kerr, Hope Robins, Myoung Hoon Ha, Annalise Ceddia, Travis L. Dutka, Lucille Chapuis   +9 more
wiley   +1 more source

Ingestive Behavior and Body Development of Backgrounded Heifers From Three Genotypes in the Brazilian Pantanal

Animal Research and One Health, EarlyView.
Nelore (N) and Nelore × Pantaneiro (NP) heifers exhibited similar grazing times, which were higher compared with Nelore × Angus (NA) heifers. Nelore heifers showed higher wither height and hip height values compared with NP heifers. The average values for NA heifers did not differ from the other genotypes. It was observed that chest depth, heart girth,
Maria C. E. Queiroz, Aylpy R. D. Santos, Marcelo Vedovatto, André L. J. Ferraz, Evellyn R. F. Bastianel, Marcus V. M. Oliveira, Rosana M. S. Arruda, Dalton M. Oliveira   +7 more
wiley   +1 more source

Advanced Imaging and Cytometric Techniques to Characterize Lipid Accumulation in Wolman Disease

Cytometry Part A, EarlyView.
ABSTRACT Wolman disease (WD) is a severe lysosomal storage disorder characterized by fatal lipid accumulation caused by the deficiency of a lipid metabolic enzyme, Lysosomal Acid Lipase (LAL), involved in the lysosomal hydrolysis of cholesterols and triglycerides.
Marine Laurent, Jérémie Cosette, Giulia Pavani, Sarah Bayol, Christine Jenny, Rim Harb, Julie Oustelandt, Anais Brassier, Daniel Stockholm, Mario Amendola   +9 more
wiley   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

Drug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy, Diana Ramírez‐Hernández, Diego Lezama‐Martínez, Benjamín Velasco‐Bejarano   +3 more
wiley   +1 more source

The pulmonary artery pulsatility index in patients with severe aortic stenosis undergoing valve replacement

ESC Heart Failure, EarlyView.
Abstract Background and aims The pulmonary artery pulsatility index (PAPi), that is, the pulmonary artery pulse pressure (PAPP) divided by the mean right atrial pressure (mRAP), is an increasingly used invasive index of right ventricular function. We sought to assess the prognostic impact of the PAPi in unselected patients with aortic stenosis (AS ...
Laura A. Rechsteiner, Lukas Weber, Philipp K. Haager, Johannes Rigger, Joannis Chronis, Peter Ammann, Roman Brenner, Martin O. Schmiady, Hans Rickli, Micha T. Maeder   +9 more
wiley   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice

Glia, EarlyView.
Absence of DBN leads to larger spinal lesions, immune cell infiltration and attenuated astrocyte reactivity in the early phase post SCI. Absence of DBN leads to greater neurodegeneration, underscoring its importance in tissue repair. ABSTRACT Spinal cord injury (SCI) results in significant disruption of nerve fibers responsible for transmitting signals
Barbora Smejkalová, Marta Ornaghi, Kateřina Štěpánková, Juliane Schiweck, Lucia Machová Urdzíková, Robert Huelse, Susanne Mueller, Philipp Boehm‐Sturm, Jessica C. F. Kwok, James Fawcett, Kai Murk, Britta J. Eickholt, Pavla Jendelová   +12 more
wiley   +1 more source

Is amnioinfusion for intrapartum variable decelerations effective? Evaluation of the total deceleration area: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Data regarding the efficiency of amnioinfusion in the presence of recurrent variable decelerations (VD) are limited. Total deceleration area (TDA) has been shown to be a useful indicator of both intrapartum fetal acid–base status and neonatal morbidity.
Gal Cohen, Nofar Bar Noy‐Traub, Hanoch Schreiber, Tal Biron‐Shental, Hila Shalev‐Ram, Michal Kovo, Dorit Ravid   +6 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source