Results 51 to 60 of about 99,358 (330)
Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors [PDF]
Dysregulation of the cell cycle and cyclin-dependent kinases (cdks) is a hallmark of cancer cells. Intervention with cdk function is currently evaluated as a therapeutic option in many cancer types including neuroblastoma (NB), a common solid tumor of ...
Eggert, Angelika +8 more
core +2 more sources
Current and Future Treatment Strategies for Rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last four decades, there have been no significant improvements in clinical outcomes
Celine Y. Chen +3 more
semanticscholar +1 more source
Rhabdomyosarcoma of the kidney
Rhabdomyosarcoma is considered the most common soft tissue sarcoma arising in patients younger than 15 years old, accounting for 5%–10% of childhood solid tumors. Sarcoma of the kidney represents 1% of all primary renal malignancies.
Alaa Samkari, Haneen Al-Maghrabi
doaj +1 more source
Pediatric malignancies are thought to be risk factors of second malignant neoplasms. However, lung cancer associated with rhabdomyosarcoma is extremely rare.
Tatsuo Furuya +8 more
doaj +1 more source
Dedifferentiation of an intracranial leptomeningeal solitary fibrous tumor to a rhabdomyosarcoma
Solitary fibrous tumors are fibroblastic mesenchymal neoplasms that also include what was previously known as hemangiopericytoma. Dedifferentiation of solitary fibrous tumors is rare and usually manifests as a high-grade sarcoma.
Roa Alqabbani +3 more
doaj +1 more source
Breast metastasis from multiple primary rhabdomyosarcoma in upper extremity
We report a 16-year-old girl with a multiple primary rhabdomyosarcoma of right upper extremity who developed contralateral breast metastasis in her clinical course.
Ramesh Omranipour, Mohamad Reza Hadi
doaj +1 more source
Epidemiology, Incidence, and Survival of Rhabdomyosarcoma Subtypes: SEER and ICES Database Analysis
Rhabdomyosarcoma is the most common soft‐tissue sarcoma in children and adolescents and accounts for 3% of all pediatric tumors. Subtypes include alveolar, spindle cell, embryonal, mixed‐type, pleomorphic, and rhabdomyosarcoma with ganglionic ...
Kamil M. Amer +11 more
semanticscholar +1 more source
BMN673 sensitizes rhabdomyosarcoma tumors to irradiation in vivo [PDF]
Bone and soft tissue sarcomas are mesenchymal tumors that occur rarely in adults, representing only 1% of total malignancies, but comprise up to 13% of malignant tumors in children.1 Rhabdomyosarcoma, a soft tissue sarcoma that commonly affects children,
Jacob, Connor
core
How to target apoptosis signaling pathways for the treatment of pediatric cancers [PDF]
Apoptosis represents one of the most important forms of cell death in higher organisms and is typically dysregulated in human cancers, including pediatric tumors.
Fulda, Simone
core +2 more sources
Simple Summary This article summarises the international Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) clinical trial for patients with rhabdomyosarcoma.
J. Chisholm +26 more
semanticscholar +1 more source

