Results 51 to 60 of about 99,358 (330)

Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors [PDF]

open access: yes, 2015
Dysregulation of the cell cycle and cyclin-dependent kinases (cdks) is a hallmark of cancer cells. Intervention with cdk function is currently evaluated as a therapeutic option in many cancer types including neuroblastoma (NB), a common solid tumor of ...
Eggert, Angelika   +8 more
core   +2 more sources

Current and Future Treatment Strategies for Rhabdomyosarcoma

open access: yesFrontiers in Oncology, 2019
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last four decades, there have been no significant improvements in clinical outcomes
Celine Y. Chen   +3 more
semanticscholar   +1 more source

Rhabdomyosarcoma of the kidney

open access: yesJournal of Pediatric Surgery Case Reports, 2018
Rhabdomyosarcoma is considered the most common soft tissue sarcoma arising in patients younger than 15 years old, accounting for 5%–10% of childhood solid tumors. Sarcoma of the kidney represents 1% of all primary renal malignancies.
Alaa Samkari, Haneen Al-Maghrabi
doaj   +1 more source

Synchronous bilateral lung adenocarcinomas associated with vulvar rhabdomyosarcoma in a 15-year-old girl

open access: yesJournal of Pediatric Surgery Case Reports, 2018
Pediatric malignancies are thought to be risk factors of second malignant neoplasms. However, lung cancer associated with rhabdomyosarcoma is extremely rare.
Tatsuo Furuya   +8 more
doaj   +1 more source

Dedifferentiation of an intracranial leptomeningeal solitary fibrous tumor to a rhabdomyosarcoma

open access: yesHuman Pathology Reports, 2022
Solitary fibrous tumors are fibroblastic mesenchymal neoplasms that also include what was previously known as hemangiopericytoma. Dedifferentiation of solitary fibrous tumors is rare and usually manifests as a high-grade sarcoma.
Roa Alqabbani   +3 more
doaj   +1 more source

Breast metastasis from multiple primary rhabdomyosarcoma in upper extremity

open access: yesClinics and Practice, 2012
We report a 16-year-old girl with a multiple primary rhabdomyosarcoma of right upper extremity who developed contralateral breast metastasis in her clinical course.
Ramesh Omranipour, Mohamad Reza Hadi
doaj   +1 more source

Epidemiology, Incidence, and Survival of Rhabdomyosarcoma Subtypes: SEER and ICES Database Analysis

open access: yesJournal of Orthopaedic Research, 2019
Rhabdomyosarcoma is the most common soft‐tissue sarcoma in children and adolescents and accounts for 3% of all pediatric tumors. Subtypes include alveolar, spindle cell, embryonal, mixed‐type, pleomorphic, and rhabdomyosarcoma with ganglionic ...
Kamil M. Amer   +11 more
semanticscholar   +1 more source

BMN673 sensitizes rhabdomyosarcoma tumors to irradiation in vivo [PDF]

open access: yes, 2020
Bone and soft tissue sarcomas are mesenchymal tumors that occur rarely in adults, representing only 1% of total malignancies, but comprise up to 13% of malignant tumors in children.1 Rhabdomyosarcoma, a soft tissue sarcoma that commonly affects children,
Jacob, Connor
core  

How to target apoptosis signaling pathways for the treatment of pediatric cancers [PDF]

open access: yes, 2013
Apoptosis represents one of the most important forms of cell death in higher organisms and is typically dysregulated in human cancers, including pediatric tumors.
Fulda, Simone
core   +2 more sources

Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

open access: yesCancers
Simple Summary This article summarises the international Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) clinical trial for patients with rhabdomyosarcoma.
J. Chisholm   +26 more
semanticscholar   +1 more source

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