Family level phylogenies reveal modes of macroevolution in RNA viruses [PDF]
, 2010 Despite advances in understanding the patterns and processes of microevolution in RNA viruses, little is known about the determinants of viral diversification at the macroevolutionary scale.
Holmes, Edward +2 more
core +3 more sources
The ovarian cancer oncobiome. [PDF]
, 2017 Humans and other mammals are colonized by microbial agents across the kingdom which can represent a unique microbiome pattern. Dysbiosis of the microbiome has been associated with pathology including cancer.
Alwine, J.C. +7 more
core +2 more sources
Phylodynamics of vampire bat-transmitted rabies in Argentina [PDF]
, 2014 Common vampire bat populations distributed from Mexico to Argentina are important rabies reservoir hosts in Latin America. The aim of this work was to analyse the population structure of the rabies virus (RABV) variants associated with vampire bats in ...
Beltran, F. +9 more
core +1 more source
Selection of single-chain antibodies that specifically interact with vesicular stomatitis virus (VSV) nucleocapsid and inhibit viral RNA synthesis. [PDF]
, 2005 International audienceThe RNA genome of non-segmented negative-strand RNA viruses is completely covered by the nucleoprotein (N) forming a ribonucleoprotein complex, the nucleocapsid.
Cortay, Jean-Claude +2 more
core +3 more sources
Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics. [PDF]
, 2015 The order Mononegavirales includes five families: Bornaviridae, Filoviridae, Nyamaviridae, Paramyxoviridae, and Rhabdoviridae. The genome of these viruses is one molecule of negative-sense single strand RNA coding for five to ten genes in a conserved ...
Cattaneo, Roberto +2 more
core +2 more sources
Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae). [PDF]
, 2009 BACKGROUND: ADARs are RNA editing enzymes that target double stranded RNA and convert adenosine to inosine, which is read by translation machinery as if it were guanosine.
Carpenter, Jennifer A +4 more
core +3 more sources
Analysis of mouse brain transcriptome after experimental Duvenhage virus infection shows activation of innate immune response and pyroptotic cell death pathway [PDF]
, 2018 Rabies is an important neglected disease, characterized by invariably fatal encephalitis. Several studies focus on understanding the pathogenic mechanisms of the prototype lyssavirus rabies virus (RABV) infection, and little is known about the ...
Amerongen, G. (Geert) van +8 more
core +1 more source
Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation-assay based diagnostic kit [PDF]
, 2014 Pseudotype viruses (PVs) are chimeric, replication-deficient virions that mimic wild-type virus entry mechanisms and can be safely employed in neutralisation assays, bypassing the need for high biosafety requirements and performing comparably to ...
Assar +44 more
core +3 more sources
Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene) [PDF]
, 2009 Background Borna disease virus (BDV) is the type member of the Bornaviridae, a family of viruses that induce often fatal neurological diseases in horses, sheep and other animals, and have been proposed to have roles in certain psychiatric diseases of ...
Courtney E Garry, Robert F Garry
core +3 more sources
Antiviral Immunity in the Fruit Fly, Drosophila melanogaster [PDF]
, 2017 The fruit fly, Drosophila melanogaster, is an extremely useful model to study innate immunity mechanisms. A fundamental understanding of these mechanisms as they relate to various pathogens has come to light over the past 30 years.
Carlson, Darby J. +4 more
core +2 more sources