Results 111 to 120 of about 2,812 (188)

A Genetic System for Rhesus Monkey Rhadinovirus: Use of Recombinant Virus To Quantitate Antibody-Mediated Neutralization [PDF]

Journal of Virology, 2006
ABSTRACT Rhesus monkey rhadinovirus (RRV), a simian gamma-2 herpesvirus closely related to the Kaposi sarcoma-associated herpesvirus, replicates lytically in cultured rhesus monkey fibroblasts and establishes persistence in B cells. Overlapping cosmid clones were generated that encompass the entire 130-kilobase-pair genome of RRV strain 26-95,
John P, Bilello, Jennifer S, Morgan, Blossom, Damania, Sabine M, Lang, Ronald C, Desrosiers   +4 more
openaire   +2 more sources

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV. [PDF]

PLoS Pathogens, 2018
Human gammaherpesviruses are associated with malignancies in HIV infected individuals; in macaques used in non-human primate models of HIV infection, gammaherpesvirus infections also occur.
Vickie A Marshall, Nazzarena Labo, Xing-Pei Hao, Benjamin Holdridge, Marshall Thompson, Wendell Miley, Catherine Brands, Vicky Coalter, Rebecca Kiser, Miriam Anver, Yelena Golubeva, Andrew Warner, Elaine S Jaffe, Michael Piatak, Scott W Wong, Claes Ohlen, Rhonda MacAllister, Jeremy Smedley, Claire Deleage, Gregory Q Del Prete, Jeffrey D Lifson, Jacob D Estes, Denise Whitby   +22 more
doaj   +1 more source

Unique structures in a tumor herpesvirus revealed by cryo-electron tomography and microscopy. [PDF]

, 2008
Gammaherpesviruses, including the human pathogens Epstein-Barr virus and Kaposi\u27s sarcoma-associated herpesvirus, are causative agents of lymphomas and other malignancies.
Atanasov, Ivo, Bortz, Eric, Dai, Wei, Jia, Qingmei, Li, Xudong, Liu, Jun, Shah, Sanket, Sun, Ren, Taylor, Kenneth A, Zhou, Z Hong   +9 more
core   +1 more source

Rhesus macaque rhadinovirus-associated non-Hodgkin lymphoma: animal model for KSHV-associated malignancies

Blood, 2008
Abstract Rhesus macaque rhadinovirus (RRV) is closely related to Kaposi sarcoma-associated herpesvirus (KSHV) and is associated with the development of B-cell hyperplasia and persistent lymphadenopathy resembling multicentric Castleman disease in rhesus macaques (RMs) coinfected with simian immunodeficiency virus (SIV).
Beata U, Orzechowska, Michael F, Powers, Jerald, Sprague, He, Li, Bonnie, Yen, Robert P, Searles, Michael K, Axthelm, Scott W, Wong   +7 more
openaire   +3 more sources

Rhesus Monkey Rhadinovirus ORF57 Induces gH and gL Glycoprotein Expression through Posttranscriptional Accumulation of Target mRNAs [PDF]

Journal of Virology, 2011
ABSTRACTOpen reading frame 57 (ORF57) of gamma-2 herpesviruses is a key regulator of viral gene expression. It has been reported to enhance the expression of viral genes by transcriptional, posttranscriptional, or translational activation mechanisms. Previously we have shown that the expression of gH and gL of rhesus monkey rhadinovirus (RRV), a close ...
Young C, Shin, Ronald C, Desrosiers
openaire   +2 more sources

A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products. [PDF]

PLoS Pathogens, 2018
The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus ...
Young C Shin, Georg F Bischof, William A Lauer, Lucas Gonzalez-Nieto, Eva G Rakasz, Gregory M Hendricks, David I Watkins, Mauricio A Martins, Ronald C Desrosiers   +8 more
doaj   +1 more source

Modulation of the Nuclear Transcription Factor of Activated T Cells by Duck Hepatitis B Virus [PDF]

, 2009
During infection with hepadnaviruses besides the infectious agent a high number of subviral particles without nucleocapsids are produced, which are able to change the infection dramatically. In addition, it was observed that the activation of the nuclear
Alicja Iwanski, Christine Loscher, Michael Bruns, Schau-Feng Chang, Urte Matschl   +4 more
core  

Molecular Characterization of the Rhesus Rhadinovirus (RRV) ORF4 Gene and the RRV Complement Control Protein It Encodes [PDF]

Journal of Virology, 2007
ABSTRACTThe diversity of viral strategies to modulate complement activation indicates that this component of the immune system has significant antiviral potential. One example is the Kaposi's sarcoma-associated herpesvirus (KSHV) complement control protein (KCP), which inhibits progression of the complement cascade. Rhesus rhadinovirus (RRV), like KSHV,
Mark, L, Spiller, OB, Okroj, M, Chanas, S, Aitken, JA, Wong, SW, Damania, B, Blom, AM, Blackbourn, DJ   +8 more
openaire   +3 more sources

Indigenous house mice dominate small mammal communities in northern Afghan military bases

BMC Zoology, 2017
Background Small mammals are important reservoirs for pathogens in military conflicts and peacekeeping operations all over the world. This study investigates the rodent communities in three military bases in Northern Afghanistan.
Christoph Gertler, Mathias Schlegel, Miriam Linnenbrink, Rainer Hutterer, Patricia König, Bernhard Ehlers, Kerstin Fischer, René Ryll, Jens Lewitzki, Sabine Sauer, Kathrin Baumann, Angele Breithaupt, Michael Faulde, Jens P. Teifke, Diethard Tautz, Rainer G. Ulrich   +15 more
doaj   +1 more source

Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques

Virology, 2010
Rhesus rhadinovirus (RRV), a primate gamma-herpesvirus related to human Kaposi's sarcoma-associated herpesvirus (KSHV), causes a similar pattern of pathogenesis. Previously, RRV was shown to express 7 pre-microRNAs (pre-miRNAs) in latently infected cells.
Umbach, Jennifer L., Strelow, Lisa I., Wong, Scott W., Cullen, Bryan R.   +3 more
openaire   +2 more sources