Rhesus monkey rhadinovirus uses eph family receptors for entry into B cells and endothelial cells but not fibroblasts. [PDF]
PLoS Pathogens, 2013 Cellular Ephrin receptor tyrosine kinases (Ephrin receptors, Ephs) were found to interact efficiently with the gH/gL glycoprotein complex of the rhesus monkey rhadinovirus (RRV).
Alexander S Hahn, Ronald C Desrosiers
doaj +10 more sources
Rhadinovirus host entry by co-operative infection.
PLoS Pathogens, 2015 Rhadinoviruses establish chronic infections of clinical and economic importance. Several show respiratory transmission and cause lung pathologies. We used Murid Herpesvirus-4 (MuHV-4) to understand how rhadinovirus lung infection might work.
Clara Lawler +3 more
doaj +5 more sources
Commentary on the Regulation of Viral Proteins in Autophagy Process [PDF]
BioMed Research International, Volume 2014, Issue 1, 2014., 2014 The ability to subvert intracellular antiviral defenses is necessary for virus to survive as its replication occurs only in the host cells. Viruses have to modulate cellular processes and antiviral mechanisms to their own advantage during the entire ...
Cheng, Ching-Yuan +2 more
core +4 more sources
Novel γ-2-Herpesvirus of the Rhadinovirus 2 Lineage in Gibbons
Emerging Infectious Diseases, 2004 We obtained 475 nucleotides of the DNA polymerase gene of a novel human herpesvirus 8 homolog sequence in a gibbon. The finding of this new gibbon virus, which clusters with a related chimpanzee virus in the rhadinovirus 2 genogroup, suggests the ...
Renan Duprez +3 more
doaj +3 more sources
Detection of a novel gammaherpesvirus (genus Rhadinovirus) in wild muntjac deer in Northern Ireland [PDF]
Archives of Virology, 2017 This study represents the initial part of an investigation into the potential for non-native, wild, free-living muntjac deer (Muntiacus reevesi) to carry viruses that could be a threat to livestock.
A Barlow +24 more
core +6 more sources
Viral FLICE inhibitory protein of Rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation [PDF]
Infectious Agents and Cancer, 2012 Rhesus monkey rhadinovirus (RRV) is a gamma-2 herpesvirus closely related to human herpesvirus 8 (HHV8). RRV encodes viral FLICE inhibitory protein (vFLIP), which has death effector domains. Little is known about RRV vFLIP. This study intended to examine
Ritthipichai Krit +3 more
doaj +5 more sources
Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV). [PDF]
PLoS Pathogens, 2021 The rhesus monkey rhadinovirus (RRV), a γ2-herpesvirus of rhesus macaques, shares many biological features with the human pathogenic Kaposi's sarcoma-associated herpesvirus (KSHV).
Anna K Großkopf +5 more
doaj +5 more sources
Myelin‐specific T cells in animals with Japanese macaque encephalomyelitis
Annals of Clinical and Translational Neurology, 2021 Objective To determine whether animals with Japanese macaque encephalomyelitis (JME), a spontaneous demyelinating disease similar to multiple sclerosis (MS), harbor myelin‐specific T cells in their central nervous system (CNS) and periphery.
Aparna N. Govindan +13 more
doaj +2 more sources
Model Systems of Gammaherpesvirus Infection, Immunity, and Disease. [PDF]
J Med VirolABSTRACT Epstein‐Barr virus (EBV) and Kaposi's sarcoma‐associated herpesvirus (KSHV) are oncogenic human gammaherpesviruses (GHVs) associated with a broad spectrum of malignancies and chronic diseases. However, direct studies of these viruses in humans are limited by ethical constraints, technical challenges, and their strict species specificity.
Gupta A, Li R, Shair K, Gao SJ.
europepmc +2 more sources
E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation
Viruses, 2023 For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald +5 more
doaj +1 more source