Results 21 to 30 of about 2,812 (188)

Rhesus macaque rhadinovirus-associated disease [PDF]

Current Opinion in Virology, 2013
Rhesus macaque rhadinovirus (RRV) is a gamma-2 herpesvirus that naturally infects rhesus macaque (RM) monkeys and is closely related to human herpesvirus-8 (HHV-8)/Kaposi's sarcoma-associated herpesvirus (KSHV). Infection of immunodeficient RM induces disease in infected RM that resembles KSHV-associated pathologies.
Ryan D, Estep, Scott W, Wong
openaire   +2 more sources

Macaque homologs of EBV and KSHV show uniquely different associations with simian AIDS-related lymphomas. [PDF]

PLoS Pathogens, 2012
Two gammaherpesviruses, Epstein-Barr virus (EBV) (Lymphocryptovirus genus) and Kaposi's sarcoma-associated herpesvirus (KSHV) (Rhadinovirus genus) have been implicated in the etiology of AIDS-associated lymphomas.
A Gregory Bruce, Helle Bielefeldt-Ohmann, Serge Barcy, Angela M Bakke, Patrick Lewis, Che-Chung Tsai, Robert D Murnane, Timothy M Rose   +7 more
doaj   +1 more source

Sex‐specific differences and predictors of echocardiographic measures of diastolic dysfunction in rhesus macaques (Macaca mulatta)

Journal of Medical Primatology, Volume 52, Issue 6, Page 374-383, December 2023., 2023
Abstract Background Diastolic dysfunction in humans is an age‐related process with an overrepresentation in women. In rhesus macaques (Macaca mulatta), the incidence and predictors of diastolic dysfunction have yet to be reported. Methods Data from routine echocardiographic evaluations on clinically healthy rhesus macaques was obtained and used for ...
Victor N. Rivas, Yu Ueda, Joshua A. Stern   +2 more
wiley   +1 more source

Whole-Genome Transcription Profiling of Rhesus Monkey Rhadinovirus [PDF]

Journal of Virology, 2005
ABSTRACT Rhesus monkey rhadinovirus (RRV) and Kaposi's sarcoma-associated herpesvirus (KSHV; also called human herpesvirus 8) belong to the gamma-2 grouping of herpesviruses. RRV and KSHV share a high degree of sequence similarity, and their genomes are organized in a similar fashion.
Dirk P, Dittmer, Carlos M, Gonzalez, Wolfgang, Vahrson, Scott M, DeWire, Rebecca, Hines-Boykin, Blossom, Damania   +5 more
openaire   +2 more sources

Viral codon optimization on SARS‐CoV‐2 Spike boosts immunity in the development of COVID‐19 mRNA vaccines

Journal of Medical Virology, Volume 95, Issue 10, October 2023., 2023
Abstract Life‐long persistent herpesviruses carry “trans‐inducers” to overcome the unusual codon usage of their glycoproteins for efficient expression. Strikingly, this “trans‐inducibility” can be achieved by simply changing the codon‐usage of acute virus glycoproteins to that of persistent herpesvirus glycoproteins with herpesviral trans‐inducer. Here,
Chih‐Jen Lai, Dokyun Kim, Seokmin Kang, Kun Li, Inho Cha, Akimi Sasaki, Jose Porras, Tian Xia, Jae U. Jung   +8 more
wiley   +1 more source

Rhesus Monkey Rhadinovirus Isolated from Hemangioma Tissue

Microbiology Resource Announcements, 2020
We isolated a rhesus monkey rhadinovirus, isolate RRVmmu 209-07, from hemangioma tissue. The virion DNA was sequenced by Illumina-based sequencing. Isolate RRVmmu 209-07 is highly similar overall to RRV 26-95, but considerable differences exist in the 3′ region of the genome.
Armin Ensser, Koji Yasuda, William Lauer, Ronald C. Desrosiers, Alexander S. Hahn   +4 more
openaire   +2 more sources

Species Specificity of Macaque Rhadinovirus Glycoprotein B Sequences [PDF]

Journal of Virology, 2000
ABSTRACT All members of the Herpesviridae family contain sequences for a highly conserved glycoprotein B (gB) gene. We investigated the phylogenetic relationships of gB sequences from eight independent rhadinovirus isolates obtained from three species: rhesus ( Macaca mulatta ...
M R, Auerbach, S C, Czajak, W E, Johnson, R C, Desrosiers, L, Alexander   +4 more
openaire   +2 more sources

Glucose and mannose analogs inhibit KSHV replication by blocking N‐glycosylation and inducing the unfolded protein response

Journal of Medical Virology, Volume 95, Issue 1, January 2023., 2023
Abstract Kaposi's sarcoma‐associated herpesvirus (KSHV) is the etiological agent for Kaposi's sarcoma (KS), an HIV/AIDS‐associated malignancy. Effective treatments against KS remain to be developed. The sugar analog 2‐deoxy‐ d‐glucose (2‐DG) is an anticancer agent that is well‐tolerated and safe in patients and was recently demonstrated to be a potent ...
Mariana Schlesinger, Christian McDonald, Anuj Ahuja, Carolina Alejandra Alvarez Canete, Zelmira Nuñez del Prado, Julian Naipauer, Theodore Lampidis, Enrique A. Mesri   +7 more
wiley   +1 more source

The Modulation of Apoptotic Pathways by Gammaherpesviruses [PDF]

, 2016
Apoptosis or programmed cell death is a tightly regulated process fundamental for cellular development and elimination of damaged or infected cells during the maintenance of cellular homeostasis. It is also an important cellular defense mechanism against
Prerna Dabral, Roxanne Strahan, Shuvomoy Banerjee, Subhash C. Verma, Timsy Uppal   +4 more
core   +6 more sources

Molecular detection of two new putative species of gammaherpesvirus in petaurid possums

Australian Veterinary Journal, Volume 100, Issue 11, Page 562-565, November 2022., 2022
A molecular survey of herpesviruses in Australian native mammals was conducted, spanning 260 individuals from 27 species. Among the herpesviruses detected, a putative new gammaherpesvirus species was detected in the yellow‐bellied glider (Petaurus australis), and another in the critically endangered Leadbeater's possum (Gymnobelideus leadbeateri).
JK Douch, JM Devlin, P Whiteley, CA Hartley, PK Vaz   +4 more
wiley   +1 more source