Results 61 to 70 of about 359,275 (203)

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

Advanced Science, Volume 12, Issue 41, November 6, 2025.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan, Yinuo Liu, Lu‐ping Chi, Chaofan Yang, Shengying Li, Wei Zhang   +5 more
wiley   +1 more source

Network pharmacology and molecular simulations reveal multi-target neuroprotective potential of Rhamnolipid and Surfactin against Alzheimer’s disease

Brain Research Bulletin
Background: Alzheimer’s disease (AD), the primary cause of dementia and lacks potent therapeutic interventions. Natural biosurfactants containing Surfactin and Rhamnolipid, with neuroprotective capability and anti-inflammatory, extend favorable multi ...
Shabir Ahmad Usmani, Saqib Ishaq, Abdul Majeed, Qamar Zaman, Abdul Aziz, Sajida Afzal, Raheel Tahir, Ajaz Ahmad, Amin Ullah   +8 more
doaj   +1 more source

Rhamnolipid and lipase production by Pseudomonas aeruginosa san-ai: the process comparison analysis by statistical approach [PDF]

Hemijska Industrija, 2013
Pseudomonas aeruginosa was repeatedly reported as powerful producer of rhamnolipid biosurfactants as well as producer of hydrolytic enzymes. In this study effects of four fermentation factors were evaluated using response surface methodology and ...
Jakovetić Sonja M., Knežević-Jugović Zorica D., Grbavčić Sanja Ž., Bezbradica Dejan I., Avramović Nataša S., Karadžić Ivanka M.   +5 more
doaj   +1 more source

Salt‐Induced Modulation of Self‐Assembly in C8‐10 AlkylPolyGlucoside/Fatty Alcohol Formulations

ChemPlusChem, Volume 90, Issue 10, October 9, 2025.
Salt's effect on the APG:1‐Dodecanol system was studied. Small‐angle X‐ray scattering showed salt increased interparticle correlation, leading to higher structural organization at higher salt concentrations. This correlates with observed viscoelastic properties. Cleaning efficiency tests were also conducted on samples.
Lorenzo Veronico, Luigi Gentile
wiley   +1 more source

Rhamnolipids as Green Stabilizers of nZVI and Application in the Removal of Nitrate From Simulated Groundwater

Frontiers in Bioengineering and Biotechnology, 2022
Environmental contamination caused by inorganic compounds is a major problem affecting soils and surface water. Most remediation techniques are costly and generally lead to incomplete removal and production of secondary waste.
Cinthia Cristine Moura, Ana Maria Salazar-Bryam, Rodolfo Debone Piazza, Caio Carvalho dos Santos, Miguel Jafelicci, Rodrigo Fernando Costa Marques, Rodrigo Fernando Costa Marques, Jonas Contiero, Jonas Contiero   +8 more
doaj   +1 more source

Study on the Preparation of Citrus Essential Oil Microemulsion and Its Effect on the Preservation of Fresh‐Cut Apples

Food Safety and Health, Volume 3, Issue 4, Page 646-658, October 2025.
We successfully fabricated a thermodynamically stable microemulsion system encapsulating citrus essential oil, demonstrating potent free radical scavenging capacity. This formulation effectively inhibits the activity of browning‐related enzymes (polyphenol oxidase and peroxidase) in fresh‐cut apples, thereby preserving their postharvest quality and ...
Xinyu Feng, Meng Qi, Xiaoshuang Zheng, Jun Guo   +3 more
wiley   +1 more source

Transcriptomic Analyses Unveil Hydrocarbon Degradation Mechanisms in a Novel Polar Rhodococcus sp. Strain R1B_2T From a High Arctic Intertidal Zone Exposed to Ultra‐Low Sulphur Fuel Oil

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Cold‐adapted Rhodococcus sp. strain R1B_2T from Arctic Tupirvik Beach (Northwest Passage) degrades short‐ to long‐chain hydrocarbons in summer seawater (−1°C to 5°C) via a synergistic activity of key hydrocarbon degradation genes (alkB, CYP153, almA, and ladA), with rhlABCR‐linked rhamnolipid production supporting biodegradation.
Nastasia J. Freyria, Antoine‐Olivier Lirette, Brady R. W. O'Connor, Charles W. Greer, Lyle G. Whyte   +4 more
wiley   +1 more source

Exploring the world of rhamnolipids: A critical review of their production, interfacial properties, and potential application [PDF]

, 2023
Eduardo Guzmán, Francisco Ortega, Ramón G. Rubio   +2 more
openalex   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Exploiting the Natural Diversity of RhlA Acyltransferases for the Synthesis of the Rhamnolipid Precursor 3-(3-Hydroxyalkanoyloxy)Alkanoic Acid

Applied and Environmental Microbiology, 2020
The RhlA specificity explains the observed differences in 3-(3-hydroxyalkanoyloxy)alkanoic acid (HAA) congeners. Whole-cell catalysts can now be designed for the synthesis of different congener mixtures of HAAs and rhamnolipids, thereby contributing to ...
Andrea Germer, T. Tiso, Conrad Müller, Beate Behrens, Christian Vosse, K. Scholz, Matti Froning, H. Hayen, L. Blank   +8 more
semanticscholar   +1 more source