Results 11 to 20 of about 179,911 (330)

Identifying rhesus macaque gene orthologs using heterospecific human CNV probes [PDF]

open access: yesGenomics Data, 2015
We used the Affymetrix® Genome-Wide Human SNP Array 6.0 to identify heterospecific markers and compare copy number and structural genomic variation between humans and rhesus macaques. Over 200,000 human copy number variation (CNV) probes were mapped to a
Jillian Ng   +4 more
doaj   +3 more sources

Intercenter reliability and validity of the rhesus macaque GeneChip

open access: yesBMC Genomics, 2007
Background The non-human primate (NHP) research community has been intensely interested in obtaining whole-genome expression arrays for their work. Recently, novel approaches were used to generate the DNA sequence information for a rhesus GeneChip.
Duan Fenghai   +3 more
doaj   +3 more sources

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Middle East Respiratory Syndrome, caused by the MERS coronavirus (MERS-CoV), continues to cause severe respiratory disease with a high case fatality rate.
E. de Wit   +8 more
semanticscholar   +1 more source

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

open access: yesScience, 2020
Immunity from reinfection One of the many open questions about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is whether an individual who has cleared the virus can be infected a second time and get sick. Chandrashekar et al.
A. Chandrashekar   +52 more
semanticscholar   +1 more source

Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

open access: yesNature Communications, 2021
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis of emerging diseases and to assess the safety ...
F. J. Salguero   +63 more
semanticscholar   +1 more source

Respiratory disease in rhesus macaques inoculated with SARS-CoV-2

open access: yesNature, 2020
An outbreak of coronavirus disease 2019 (COVID-19), which is caused by a novel coronavirus (named SARS-CoV-2) and has a case fatality rate of approximately 2%, started in Wuhan (China) in December 20191,2.
V. Munster   +16 more
semanticscholar   +1 more source

Relationship between the ABO blood group and lung cancer susceptibility

open access: yesMedical Journal of Babylon, 2021
Background: Lung cancer (LC) is one of the well-known fatal malignant neoplasms worldwide. Objective: The objective of this study was to determine the potential relationship between ABO and Rhesus blood groups with LC.
Zahir Salih Hussein
doaj   +1 more source

ABO blood groups, rhesus factor and pemphigus

open access: yesIndian Journal of Dermatology, 2007
Background: Pemphigus is an autoimmune blistering disease of the skin and mucous membranes with significant mortality and morbidity. Genetic factors are known to be involved in pemphigus.
Valikhani Mahin   +4 more
doaj   +1 more source

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

open access: yesNature, 2020
Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed. While many investigational, approved, and repurposed drugs have been suggested as potential treatments, preclinical data from animal models can guide the search for ...
Brandi N. Williamson   +21 more
semanticscholar   +1 more source

3-2-Rhesus-2.jpeg

open access: yes, 2021
The rhesus macaque is one of the most widely used nonhuman primate models for human diseases. Rhesus macaques share ~95% genetic homology with humans and have been designated as a high-priority organism for whole-genome sequencing by the National Human ...
vivian Creative (11667427)
core   +1 more source

Home - About - Disclaimer - Privacy