Results 21 to 30 of about 103,300 (196)

Characterization of Ebola Virus Disease (EVD) in Rhesus Monkeys for Development of EVD Therapeutics

Viruses, 2020
Recent Ebola virus (EBOV) outbreaks in West Africa and the Democratic Republic of the Congo have highlighted the urgent need for approval of medical countermeasures for treatment and prevention of EBOV disease (EVD).
Travis Warren, Elizabeth Zumbrun, Jessica M. Weidner, Laura Gomba, Franco Rossi, Roy Bannister, Jacqueline Tarrant, Matthew Reed, Eric Lee, Jo Lynne Raymond, Jay Wells, Joshua Shamblin, Kelly Wetzel, Ginger Donnelly, Sean Van Tongeren, Nicole Lackemeyer, Jesse Steffens, Adrienne Kimmel, Carly Garvey, Holly Bloomfield, Christiana Blair, Bali Singh, Sina Bavari, Tomas Cihlar, Danielle Porter   +24 more
doaj   +1 more source

Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA

Molecular Therapy: Nucleic Acids, 2015
One possible treatment for Huntington's disease involves direct infusion of a small, interfering RNA (siRNA) designed to reduce huntingtin expression into brain tissue from a chronically implanted programmable pump.
Richard Grondin, Pei Ge, Qingmin Chen, Jessica E Sutherland, Zhiming Zhang, Don M Gash, David K Stiles, Gregory R Stewart, Dinah W Y Sah, William F Kaemmerer   +9 more
doaj   +1 more source

B-Virus and Free-Ranging Macaques, Puerto Rico

Emerging Infectious Diseases, 2004
In Puerto Rico, risk for transmission of B-virus from free-ranging rhesus monkeys to humans has become a serious challenge. An incident with an injured rhesus monkey, seropositive for B-virus, resulted in inappropriate administration of antiviral ...
Kristen Jensen, Francisco Alvarado-Ramy, Janis González-Martínez, Edmundo Kraiselburd, Johnny Rullán   +4 more
doaj   +1 more source

Relationship between the ABO/Rh Blood Group Factors with Coronavirus Disease 2019 Severity and Mortality among Hospitalized Patients in Algeria: A Single-center Study

Journal of Advanced Lung Health
Introduction: The novel coronavirus causes the deadly disease, severe acute respiratory syndrome (SARS). Therefore, it is necessary to identify prognostic factors for patients hospitalized with SARS-coronavirus-2 infection to identify patients with ...
Abdelbassat Ketfi, Karima Zouai, Yacine Djagheri, Kamel Djenouhat, Rama Touahri   +4 more
doaj   +1 more source

Conformation of HIV-1 Envelope Governs Rhesus CD4 Usage and Simian-Human Immunodeficiency Virus Replication

mBio, 2022
Infection of rhesus macaques with simian-human immunodeficiency viruses (SHIVs) is the preferred model system for vaccine development because SHIVs encode human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Envs)—a key target of HIV-1 ...
Geraldine Vilmen, Anna C. Smith, Hector Cervera Benet, Rajni Kant Shukla, Ross C. Larue, Alon Herschhorn, Amit Sharma   +6 more
doaj   +1 more source

Conformal Thermoreversible Gelatin‐Based Gel for High‐Fidelity Electrophysiological Recording and Acute Peripheral Nerve Interfacing

Advanced Materials, EarlyView.
A thermoreversible gelatin‐based gel forms a soft, conformal bioelectronic interface on complex biological surfaces. The flowable precursor penetrates hair‐dense regions, solidifies in situ, and maintains low impedance through adaptive contact and hydration retention.
Ruinan Hao, Yong Yuan, Jie Gao, Tong Wang, Jinzhi Du, Feng Tian, Xiaoli Li, Ruirui Qiao, Liqun Zhang, Jiajia Xue   +9 more
wiley   +1 more source

The relationship between ABO/rhesus blood groups and type 2 diabetes mellitus in Maghnia, western Algeria

South African Family Practice, 2011
Background: To determine the relationship between ABO/rhesus (Rh) blood groups and type 2 diabetes mellitus in a western Algerian population. Method: This case-control study was conducted at the Regional Hospital Centre of Maghnia, Tlemcen, from July ...
M. Dali Sahi, A. Aour Metri, F. Belmokhtar, R. Belmokhtar, F. Bouazza   +4 more
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Successful Management of Hemolytic Anemia Due to Rh-immunization, Diagnosed Antenatally

Caucasian Medical Journal
Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in maternal-fetal medicine, despite advancements in prevention and management.
Sevinch Mahmudova, Gulnar Elizade, Nezrin Hesenli, Turab Janbakhishov, Sarkhan Elbayiyev   +4 more
doaj   +1 more source

Worse Health Status and Higher Incidence of Health Disorders in Rhesus Negative Subjects. [PDF]

PLoS ONE, 2015
Rhesus-positive and Rhesus-negative persons differ in the presence-absence of highly immunogenic RhD protein on the erythrocyte membrane. The biological function of the RhD molecule is unknown.
Jaroslav Flegr, Rudolf Hoffmann, Mike Dammann   +2 more
doaj   +1 more source