Results 201 to 210 of about 179,911 (330)

Sequence context and methylation interact to shape germline mutation rate variation at CpG sites. [PDF]

PLoS Genet
Chandra S, Gao Z.
europepmc   +1 more source

Human Coronavirus 229E Uses ORF4/4a to Antagonize the Host Restriction Factor SERINC5

MedComm, Volume 7, Issue 6, June 2026.
The seasonal human coronaviruses 229E and OC43 are common causes of mild respiratory infections but can cause severe disease in vulnerable individuals. Serine incorporator 5 (SERINC5) efficiently inhibits OC43, while hCoV‐229E uses its ORF4/4a accessory proteins to efficiently counteract this restriction by promoting relocalization of SERINC5 to ...
Qinya Xie, Sabrina Noettger, Jan Lawrenz, Sophie Stopper, Susanne Klute, Jan Münch, Dorota Kmiec, Qingxing Wang, Konstantin M. J. Sparrer, Frank Kirchhoff   +9 more
wiley   +1 more source

Correction to: Long-Term Monochromatic Light Exposure Does Not Alter Modular Chromatic Representation in the Visual Cortex of Rhesus Monkeys. [PDF]

Neurosci Bull
Zhu W, Liu Y, Chen X, Qian L, Wang W, Zou L, Lu Y, Liu R.   +7 more
europepmc   +1 more source

Bioartificial Livers Developed From Gene‐Edited Pig Hepatocyte Organoids Improve Amino Acid and Lipid Profiles in the Plasma of Patients With Liver Failure

MedComm, Volume 7, Issue 6, June 2026.
A bioartificial liver (BAL) integrating GGTA1‐knockout porcine hepatocytes and R‐spondin1‐overexpressing endothelial organoids was tested using plasma from patients with acute‐on‐chronic liver failure (ACLF). The BAL system actively modulates amino acid and lipid metabolism, enhances detoxification, partially restores overall metabolic balance, and ...
Yuting He, Yang Deng, Xinglong Zhu, Mengyu Gao, Qin Liu, Wanliu Peng, Yanyan Zhou, Lang Bai, Ji Bao   +8 more
wiley   +1 more source

Comparative analysis of gut microbiota and host phenotypic characteristics across enterotype-like clusters in cynomolgus and rhesus macaques. [PDF]

Front Microbiol
Choi J, Shim K, Bae GS, Jeon E, Hwang EH, Kim G, Baek SH, Hong JJ, Kim DS, Kim SH, Koo BS.   +10 more
europepmc   +1 more source

Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment

Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1488-1495, June 2026.
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier, Christina Bolte, Jan‐Ole Radecke, Feline Hamami, Andreas Sprenger, Christoph Helmchen, Robert Chen, Marcus Callister, Talyta Cortez Grippe, Christine Klein, Norbert Brüggemann, Tobias Bäumer, Alexander Münchau, Anne Weissbach   +13 more
wiley   +1 more source

A review of chronic enterocolitis of rhesus macaques (<i>Macaca mulatta</i>) and potential as a naturally occurring model for post-infectious irritable bowel syndrome. [PDF]

Front Vet Sci
Bacon RL, Lawhon SD, Gray SB, Hodo CL.
europepmc   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Encephalomyocarditis virus (EMCV): An overlooked threat to primates. [PDF]

PLoS Negl Trop Dis
Amona I, Kumakamba C, Labarrere C, Davoust B, Fenollar F, Mediannikov O.   +5 more
europepmc   +1 more source

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

Addiction, Volume 121, Issue 6, Page 1541-1556, June 2026.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu, Chia‐Chun Hung, Marc N. Potenza, Kun‐Hsien Chou, Pei‐Lin Lee, Chu‐Chung Huang, Chiang‐Shan R. Li, Tony Szu‐Hsien Lee, Ching‐Po Lin   +8 more
wiley   +1 more source