Results 221 to 230 of about 179,911 (330)
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Age-Related Decline in Myelin Markers and Oligodendrocyte Density in Rhesus Macaque Prefrontal Cortex. [PDF]
Zhang Y +5 more
europepmc +1 more source
ABSTRACT Background Thyroid disease is reported in orangutans, but to properly diagnose and manage these disorders, reference intervals for circulating thyroid hormones are needed. Methods Commercial immunoassay kits for total thyroxine (TT4) and free thyroxine (FT4) were validated for use in orangutans (Pongo spp.).
Melissa A. Fayette +4 more
wiley +1 more source
A Conserved Natural Killer Cell Transcriptional Fingerprint in Rhesus Macaque Models of Acute Viral Infections. [PDF]
Hudson A +5 more
europepmc +1 more source
ABSTRACT Nonhuman primates (NHPs) have emerged as an indispensable model for studying HIV pathogenesis, vaccines, and therapies. The development of chimeric Simian/Human immunodeficiency viruses (SHIVs) has been constructed by inserting HIV‐1 Env into the SIV (usually SIVmac239) backbone, and these have proved essential for evaluating HIV neutralizing ...
A. J. Hessell +2 more
wiley +1 more source
ABO and RhD blood group distributions in Gansu Province, China: A retrospective study based on donor and patient data. [PDF]
Zhang X, Liu M, Liu K, He Y.
europepmc +1 more source
ABSTRACT Identifying close relatives in wild animal populations is fundamental across many research fields. Genetic estimates of relatedness have expanded rapidly in recent decades, drawing on a range of genetic data types. Here, we review their use and outline opportunities for future studies by combining two complementary approaches.
Annika Freudiger +7 more
wiley +1 more source
Preparation, Oral SNEDDS Formulation, and In Vivo Evaluation of the HIV-1 Latency-Reversing Agent EK-16A. [PDF]
Jin L +20 more
europepmc +1 more source
A Visual Behavioral Training Study of Categorical Face Pattern Recognition in Mice
Mice trained in a touchscreen face–object discrimination task generalized to novel exemplars but showed reduced performance when images were inverted or contrast‐negated. Along a continuum from pareidolia to real faces, choice behavior followed an S‐shaped curve, with mouse face–object discrimination showing patterns similar to those seen in humans ...
Yanhong Chen +5 more
wiley +1 more source

