Results 211 to 220 of about 179,911 (330)
Incidence of Spontaneous Ocular Lesions in Laboratory Animals. [PDF]
Cheng H, Gao J, Zhou Y.
europepmc +1 more source
T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett +2 more
wiley +1 more source
Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination. [PDF]
Habib R +38 more
europepmc +1 more source
ABSTRACT HIV transmission through the female and male reproductive tracts is governed by spatially organized interactions between virions, epithelial barriers, and tissue‐resident immune cells. Imaging approaches have been central to defining these earliest events, progressing from classical histology and immunohistochemistry (IHC) to modern ...
Ann M. Carias +3 more
wiley +1 more source
Chronic methanol exposure induces cognitive impairment and Alzheimer's-like pathology in rhesus monkeys. [PDF]
Li H +9 more
europepmc +1 more source
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
G. Gao +5 more
semanticscholar +1 more source
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki +8 more
wiley +1 more source
Rhesus macaques with an <i>OPA1</i> mutation demonstrate features of autosomal dominant optic atrophy. [PDF]
Jaggers TN +27 more
europepmc +1 more source
Cerebrospinal Fluid and Plasma Concentrations of Atogepant in Humans
ABSTRACT The aim of this study was to determine the cerebrospinal fluid (CSF) to plasma concentration ratio of atogepant. Healthy adult participants (N = 28) were enrolled into this phase 1, open‐label study and received atogepant 60 mg once daily for 8 days. Steady‐state atogepant concentrations were determined from CSF samples collected on Day 6 at 2
Ramesh R. Boinpally, Joel M. Trugman
wiley +1 more source

