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Epigentics in rheumatic diseases [PDF]
The human genome comprises approximately 30000 genes needed for the formation and function of approximately 1 Million proteins in the human body. Differentiation leads to the deactivation of genes that are not needed in the specific tissues or cells.
Gay, S, Jüngel, A
core +4 more sources
Autoimmune Rheumatic Diseases [PDF]
The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Nevertheless, all these conditions share similar pathophysiological mechanisms [
Juan-Manuel Anaya +3 more
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Rheumatic diseases in Africa [PDF]
Historically, rheumatic diseases have not received much attention in Africa, particularly in sub-Saharan Africa, possibly owing to a focus on the overwhelming incidence of infectious diseases and the decreased life span of the general population in this region.
Olufemi Adelowo +4 more
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Spine and Rheumatic Diseases [PDF]
Rheumatic diseases include a wide spectrum of diseases involving musculoskeletal and immune system. Spinal disorders, whether mechanical or inflammatory, are main manifestations in daily clinical practice of rheumatologists, neurologists, orthopaedics, and general physicians.
James Cheng-Chung Wei +3 more
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Yoga in Rheumatic Diseases [PDF]
Yoga is a popular activity which may be well suited for some individuals with certain rheumatic disorders. Regular yoga practice can increase muscle strength and endurance, proprioception and balance, with emphasis on movement through a full range of motion to increase flexibility and mobility.
Christopher Mill +6 more
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Frailty in Rheumatic Diseases [PDF]
Frailty is a syndrome characterized by the decline in the physiologic reserve and function of several systems, leading to increased vulnerability and adverse health outcomes. While common in the elderly, recent studies have underlined the higher prevalence of frailty in chronic diseases, independent of age.
Francesca Motta +5 more
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Photosensitivity in Rheumatic Diseases [PDF]
There have been a number of recent advances in the genetic understanding of photosensitive rheumatic diseases, especially subacute cutaneous lupus erythematosus and dermatomyositis. These advances support the concept that increased numbers of ultraviolet light-induced apoptotic cells in skin lead to a supra-threshold concentration of antigenic peptides.
Victoria P. Werth +3 more
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Glycobiology of rheumatic diseases
Glycosylation has a profound influence on protein activity and cell biology through a variety of mechanisms, such as protein stability, receptor interactions and signal transduction. In many rheumatic diseases, a shift in protein glycosylation occurs, and is associated with inflammatory processes and disease progression.
Kissel, T. +3 more
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Histopathology of the gut in rheumatic diseases [PDF]
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F. +4 more
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Rheumatic Diseases in China [PDF]
Abstract Introduction Epidemiological studies of rheumatic diseases have been conducted during the past 20 years in China. The aim of this study was to clarify prevalence rates of common rheumatic diseases in China.
Su Biao Chen +7 more
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