Results 21 to 30 of about 150,924 (298)

Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2019
Background Structural variations such as copy number variations (CNVs) have a functional impact on various human traits. This study profiled genome-wide CNVs in Korean patients with rheumatoid arthritis (RA) to investigate the efficacy of treatment with ...
Ki-Nam Gu   +19 more
doaj   +1 more source

Demyelination in rheumatic diseases [PDF]

open access: yesPostgraduate Medical Journal, 2008
Abstract Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterised by multifocal areas of demyelination in the white matter of the brain and spinal cord. Autoantibodies, for example antinuclear antibodies, can also be present.
A Theodoridou, Loukas Settas
openaire   +4 more sources

The macrophages in rheumatic diseases

open access: yesJournal of Inflammation Research, 2016
Macrophages belong to the innate immune system giving us protection against pathogens. However it is known that they are also involved in rheumatic diseases. Activated macrophages have two different phenotypes related to different stimuli: M1 (classically activated) and M2 (alternatively activated).
Magda Scarpellini   +5 more
openaire   +6 more sources

Role of raloxifene in the management of postmenopausal osteoporosis of rheumatoid arthritis patients

open access: yesEuropean Pharmaceutical Journal, 2023
Due to the severe side effects of long-term treatment using hormone replacement therapy, Raloxifene (RLX) is introduced with beneficial effects on rheumatoid arthritis (RA) for postmenopausal women.
Salari M.   +3 more
doaj   +1 more source

Reduced Humoral Response of SARS-CoV-2 Antibodies following Vaccination in Patients with Inflammatory Rheumatic Diseases—An Interim Report from a Danish Prospective Cohort Study

open access: yesVaccines, 2021
Background/Purpose: In light of the current COVID-19 pandemic, whether patients with rheumatic musculoskeletal disease (RMD) treated with conventional (cs) or biologic (b) disease-modifying drugs (DMARDs) exhibit an adequate immune response to the ...
Karen Schreiber   +8 more
doaj   +1 more source

Increased risk of malignancy in patients with systemic lupus erythematosus: population-based cohort study in Korea

open access: yesArthritis Research & Therapy, 2021
Background This study aimed to evaluate the crude incidence rates and relative risk of malignancy in Korean patients with SLE. Methods We conducted a retrospective nationwide cohort study using databases from the National Health Insurance Service in ...
Jung-Yong Han   +5 more
doaj   +1 more source

Genetics of rheumatic disease [PDF]

open access: yesArthritis Research & Therapy, 2009
Many of the chronic inflammatory and degenerative disorders that present to clinical rheumatologists have a complex genetic aetiology. Over the past decade a dramatic improvement in technology and methodology has accelerated the pace of gene discovery in complex disorders in an exponential fashion.
Alexander J. Clarke, Timothy J. Vyse
openaire   +3 more sources

A double-blind placebo-controlled randomized trial of oral saffron in the treatment of rheumatoid arthritis [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2021
Objective: Recently, saffron (Crocus sativus L. from the Iridaceae family) has been characterized by its antioxidant, anti-inflammatory and analgesic effects.
Maryam Sahebari   +8 more
doaj   +1 more source

Osteoporosis in Rheumatic Diseases

open access: yesInternational Journal of Molecular Sciences, 2019
Osteoporosis is a chronic disease characterized by an increased risk of fragility fracture. Patients affected by rheumatic diseases are at greater risk of developing osteoporosis. The purpose of the present review is to discuss the pathogenesis, epidemiology, and treatment of osteoporosis in patients affected by rheumatic diseases with special focus ...
Adami, Giovanni   +7 more
openaire   +4 more sources

Sustained Drug Free Remission of Lupus Panniculitis with Methotrexate: A Report From Nepal

open access: yesJournal of Nepal Medical Association, 2018
Cutaneous manifestations are second most common presenting feature of lupus. Discoid lupus erythematosus is the most common variant amongst all; lupus panniculitis being described in only 2-5% of cases.
Binit Vaidya   +3 more
doaj   +1 more source

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