Results 41 to 50 of about 150,924 (298)

Adjunct role of potassium-rich vegetarian diet and a novel potassium food supplement to improve pain in chronic rheumatoid arthritis on supervised standard care: a randomised controlled study

BMJ Nutrition, Prevention & Health
Introduction An earlier food survey showed dietary potassium deficiency in rheumatoid arthritis (RA).Objective To evaluate an adjunct role of oral potassium to reduce joint pain in RA.Methods 172 consenting eligible symptomatic patients (median duration ...
Arvind Chopra, Manjit Saluja, Toktam Kianifard, Sanjeev Sarmukaddam, Anuradha Venugopalan   +4 more
doaj   +1 more source

Tissue Engineering and Stem Cell Therapy in Neurogenic Bladder Dysfunction: Current and Future Perspectives

Medicina, 2023
Tissue engineering (TE) is a rapidly evolving biomedical discipline that can play an important role in treating neurogenic bladder dysfunction and compensating for current conventional options’ shortcomings. This review aims to analyze the current status
Katarina Topoliova, Stefan Harsanyi, Lubos Danisovic, Stanislav Ziaran   +3 more
doaj   +1 more source

Calprotectin in rheumatic diseases [PDF]

Experimental Biology and Medicine, 2016
Calprotectin is a heterodimer formed by two proteins, S100A8 and S100A9, which are mainly produced by activated monocytes and neutrophils in the circulation and in inflamed tissues. The implication of calprotectin in the inflammatory process has already been demonstrated, but its role in the pathogenesis, diagnosis, and monitoring of rheumatic diseases
OMETTO, FRANCESCA, Friso, Lara, Astorri, Davide, Botsios, Costantino, Raffeiner, Bernd, PUNZI, LEONARDO, DORIA, ANDREA   +6 more
openaire   +3 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis

Arthritis Research & Therapy, 2018
Background IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis.
Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae, Tae-Hwan Kim   +9 more
doaj   +1 more source

Developing a complex vocational rehabilitation intervention for patients with inflammatory arthritis: the WORK-ON study

BMC Health Services Research, 2023
Background People with inflammatory arthritis often experience challenges at work and balancing paid work and energy in everyday life. Low work ability is common, and people with inflammatory arthritis face high risks of losing their jobs and permanent ...
Christina Merete Tvede Madsen, Jette Primdahl, Ann Bremander, Linda Eggen, Jeanette Reffstrup Christensen   +4 more
doaj   +1 more source

Epidemiology of the rheumatic diseases [PDF]

Current Opinion in Rheumatology, 1993
Emerging osteoarthritis studies suggest that certain occupations are associated with a high risk for development of hip and knee osteoarthritis, at least in men. The main activities identified are regular lifting for the hip and knee bending for the knee.
openaire   +4 more sources

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett, Karl Everett, Colleen J. Maxwell, Feng Zhu, Ayesha Asaf, Ping Li, Kyla A. McKay, Yinshan Zhao, Ruth Ann Marrie   +8 more
wiley   +1 more source

A Simplified Understanding of the Black Swan: Anti-phospholipid Antibody Syndrome

Journal of Nepal Medical Association, 2019
Anti-phospholipid antibody syndrome is caused by the presence of specific antibodies against phospholipid-binding plasma proteins in serum of patient, with or without underlying autoimmune diseases, that causes prolongation of tests of coagulation.
Binit Vaidya, Shweta Nakarmi, Rakshya Joshi, Rikesh Baral   +3 more
doaj   +1 more source