Results 51 to 60 of about 142,035 (242)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han +9 more
wiley +1 more source
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
, 2006 BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources
Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source
Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research [PDF]
, 2016 No abstract ...
Buckley, Christopher D. +9 more
core +3 more sources
Arthritis Care &Research, EarlyView.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
, 1974 The 45th Annual McGuire Lecture Series has been devoted to the subject of Immunology and the Rheumatic Diseases. In this two-day period, 22 outstanding physicians in the field of immunology and rheumatology brought an up-to-date overall concept in the ...
Irby, Robert
core +1 more source
The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases [PDF]
, 2016 Dysregulation of the intestinal epithelial barrier in genetically susceptible individuals may lead to both intestinal and extraintestinal autoimmune disorders.
CICCIA, Francesco +3 more
core +1 more source
Osteoimmunology in rheumatic diseases [PDF]
Arthritis Research & Therapy, 2009 This review summarizes the recent advances of osteoimmunology, a new research field that investigates the interaction of the immune system with the skeleton. Osteoimmunology has contributed significantly to the understanding of joint destruction in rheumatoid arthritis and other forms of arthropathies.
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder +5 more
wiley +1 more source
Guidelines for the management of the foot health problems associated with rheumatoid arthritis [PDF]
, 2011 Background. Rheumatoid arthritis (RA) as a chronic systemic disease, commonly affects the feet, impacting negatively on patients' quality of life. Specialist podiatrists have a prime role to play in the assessment and management of foot and ankle ...
Bowen, C +6 more
core +1 more source