Results 71 to 80 of about 9,651,090 (393)
Allergology International, 2009 Background: Flavonoids are nutrients that exert anti-allergic effects. We investigated the preventative effect of enzymatically modified isoquercitrin (EMIQ), a flavonoid, to relieve the symptoms of Japanese cedar pollinosis. Methods: In a parallel-group,
Toru Hirano +16 more
doaj +1 more source
Role of Nigella sativa in the Management of Osteoarthritis: A Systematic Review
Traditional and Integrative Medicine, 2023 Because of the anti-inflammatory properties of thymoquinone (TQ), as the main bioactive substance of Nigella sativa, this systematic review aimed at assessing the therapeutic effects of N.
Mozhdeh Ghamari +2 more
doaj +1 more source
Glycosylation and rheumatic disease
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1998 Rheumatoid arthritis (RA) and other rheumatic diseases are associated with a significant defect in the galactosyltransferase enzyme that results in a profound change in the galactosylation of immunoglobulin G. This change has been demonstrated to be integrally associated with pathogenic mechanisms associated with inflammation in RA.
openaire +3 more sources
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
One year in review: ultrasound in arthritis [PDF]
, 2016 Musculoskeletal ultrasound (MSUS) has become a relevant part of rheumatology practice and research because it substantially allows us to optimize management of rheumatic and musculoskeletal diseases. This non-invasive imaging modality is a valuable point-
IAGNOCCO, Annamaria, Naredo, Esperanza
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Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis
Arthritis Research & Therapy, 2018 Background IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis.
Sungsin Jo +9 more
doaj +1 more source
The prevalence of rheumatic diseases in the elderly in developed countries and its evolution over time [PDF]
, 2018 Summary.: Objectives: This study aims at evaluating the prevalence of rheumatic diseases in the elderly and its evolution over time. Methods: We present a systematic international literature review of the prevalence of rheumatic diseases in the elderly ...
Mariller, Marjorie +1 more
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The adolescent with rheumatic disease [PDF]
Archives of Disease in Childhood, 1997 Adolescence is a period of emotional and physical upheaval and a time when personal identity, need for independence, and peer relationships all evolve. This transition from dependence to independence can be a difficult process for healthy teenagers. Those with chronic illness and disability have additional concerns, rendering them especially vulnerable
R, Sathananthan, J, David
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Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source