Results 111 to 120 of about 663,231 (378)

Plectranthus‐derived Abietanes as Protein Kinase C‐δ Activators: In Silico Design, Human Serum Albumin Interaction, and Stability Evaluation

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Cancer remains a major global health challenge. Among protein kinases (PKCs), PKC‐δ acts as a tumor suppressor in colon cancer and represents a valuable therapeutic target. Human serum albumin (HSA) is gaining attention as an efficient drug carrier, while Plectranthus spp. offers a rich source of bioactive compounds.
Vera M. S. Isca   +4 more
wiley   +1 more source

The great simulator [PDF]

open access: yes, 1993
Cardiac myxoma often simulates multisystem disease and initially defies diagnosis. In this paper, we present three cases of cardiac myxoma in adults.
Aquilina, Oscar   +2 more
core  

Rheumatic fever and rheumatic heart disease in Gauteng on the decline : Experience at Chris Hani Baragwanath Academic Hospital, Johannesburg. South Africa [PDF]

open access: yes, 2014
PKBackground: The incidence of rheumatic fever (RF) and its complications has waned over the past three to four decades throughout the Western world, but RF remains a problem in developing countries and in the indigenous populations of some well ...
Celliers, A M
core   +1 more source

Toxic Evaluations of Calea phyllolepis Extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate and Its In Silico Prediction of the Toxicity

open access: yesChemistry &Biodiversity, EarlyView.
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato   +6 more
wiley   +1 more source

Treatment of Rheumatic Fever [PDF]

open access: yesCirculation, 1956
The treatment of active rheumatic fever has changed little over the course of years; bed rest is believed to be necessary for the lessening of residua although there is only slight evidence for this belief. The virtues of salicylates in high and low dosage and of similar compounds, of corticotropin, cortisone and its analogues continue to be discussed ...
openaire   +3 more sources

Clinical and demographic features of 193 patients with rheumatic fever [PDF]

open access: yes, 2006
OBJECTIVE: the aim of this study was to analyze the demographic and clinical characteristics of patients with acute rheumatic fever (ARF), followed between 1995 and 2005.
Caldas, Álvaro Manuel   +4 more
core   +2 more sources

Antimicrobial Activity and Chemical Constituents of Siparuna guianensis (Siparunaceae)

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Siparuna guianensis (Siparunaceae) is an Amazonian plant known by the popular name of Negramina. There are several reports of the use of this plant in folk medicine. In the present work, we decided to study its extracts, aiming at the isolation of compounds and verifying their antimicrobial activities.
Olência Mento Manuensa Vilanculo   +7 more
wiley   +1 more source

Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes

open access: yesDrugs in R&D
Superficial infections with Streptococcus pyogenes (Strep A), pharyngitis and impetigo can induce acute rheumatic fever, an autoimmune sequela manifesting mostly with arthritis and rheumatic carditis.
Usman Nakakana   +8 more
doaj   +1 more source

The Epidemiology of Rheumatic Fever [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1941
FOR some years reasons have been obvious for promoting the public health aspects of rheumatic fever, a disease which may be classed as our third most common chronic infection (after tuberculosis and syphilis). But in spite of the obvious need, there have also been reasons why relatively little public health work has been done on rheumatic fever in this
openaire   +3 more sources

Rare presentation of an atrial myxoma in an adolescent patient: A case report and literature review [PDF]

open access: yes, 2018
BACKGROUND: Cardiac tumors are uncommon in the pediatric population. When present, cardiac manifestations stem from the tumor causing inflow or outflow obstruction.
Anwar, Shafkat   +6 more
core   +3 more sources

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