Results 91 to 100 of about 672,391 (345)

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Rheumatic Fever and Rheumatic Heart Disease a Historical Perspective

Heart Views, 2016
In March 1942, a 33-year-old woman in the USA was hospitalized for a month with a life-threatening streptococcal infection at a New Haven, Connecticut, hospital. She had streptococcal septicemia from childbirth.
R. Hajar
semanticscholar   +1 more source

Epidemiology of acute rheumatic fever and rheumatic heart disease

, 2018
This chapter outlines the current best estimates for mortality and morbidity for group A Streptococcus, acute rheumatic fever, and rheumatic heart disease and in particular highlights the disproportionate burden of disease.
Liesl Zühlke
core   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, Accepted Article.
Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz, Seza Ozen, Hacer N. Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet E. Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet O. Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Sydenham's chorea in a 16‐year‐old female from Bhutan: A case report

Clinical Case Reports
Key Clinical Message Rheumatic heart disease is a preventable disease. Patients may not present with a typical history of sore throat and polyarthritis but may present with Sydenham's chorea. We should not rely completely on clinical findings to rule out
Tshering Penjor, Thinley Dorji, Sangay Wangchuk   +2 more
doaj   +1 more source

Sixteen year retrospective analysis of rheumatic and non-rheumatic heart disease patients undergoing valve procedures at Groote Schuur Hospital first incidence single aortic and mitral valve replacement

, 2012
Includes abstract.Includes bibliographical references.Rheumatic heart disease is still the most common cause of valvular heart lesions requiring replacement or repair procedures worldwide.
Ogunrombi, Akinwumi Babatunde
core  

Real‐World Usage and Outcomes of Different Siltuximab Dosing Frequency in Idiopathic Multicentric Castleman Disease

American Journal of Hematology, EarlyView.
Yoshito Nishimura, Maria Santiago Estevez, Hakeem Asad, Thomas Habermann, Angela Dispenzieri   +4 more
wiley   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Joint WHO/ISFC Meeting on Rheumatic Fever/Rheumatic Heart Disease Control, with Emphasis on Primary Prevention, Geneva, 7-9 September 1994

, 1994
ONLINEWHO/CVD/94.1.
Joint WHO/ISFC Meeting on Rheumatic Fever/Rheumatic Heart Disease Control with Emphasis on Primary Prevention (1994: Geneva, Switzerland)
core  

Antibiotics for the primary prevention of acute rheumatic fever: a meta-analysis

BMC Cardiovascular Disorders, 2005
Background Rheumatic fever continues to put a significant burden on the health of low socio-economic populations in low and middle-income countries despite the near disappearance of the disease in the developed world over the past century.
Volmink Jimmy A, Robertson Katharine A, Mayosi Bongani M   +2 more
doaj   +1 more source