Results 71 to 80 of about 375,685 (295)
Sydenham's chorea in a 16‐year‐old female from Bhutan: A case report
Clinical Case ReportsKey Clinical Message Rheumatic heart disease is a preventable disease. Patients may not present with a typical history of sore throat and polyarthritis but may present with Sydenham's chorea. We should not rely completely on clinical findings to rule out
Tshering Penjor +2 more
doaj +1 more source
Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome
Arthritis &Rheumatology, EarlyView.Objective VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani +10 more
wiley +1 more source
Expert Perspectives: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies
Arthritis &Rheumatology, EarlyView.Treat‐to‐target has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal treat‐to‐target framework for adult IIM has not yet been ...
Shiri Keret +2 more
wiley +1 more source
Rheumatic Fever and Antibody Response to Group A Streptococcal Infections
, 2017 Rheumatic fever is non-suppurative sequel of group A streptococcal infection. It is a multifocal inflammatory disease, affecting primarily the heart, joints, skin and central nervous system occurring in 0.1% to 3% after untreated pharyngitis.
R Makaju, Ganesh Prasad Neupane, R Koju
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objective The objective of this study was to characterize the clinical, immunologic, and synovial tissue features of a patient with a systemic juvenile idiopathic arthritis (sJIA) who carries a novel heterozygous STAT5B loss‐of‐function variant (p.Gln139Ter) and whose arthritis responded markedly to interleukin‐17A (IL‐17A) inhibition.
Indira Sriram +14 more
wiley +1 more source
Antibiotics for the primary prevention of acute rheumatic fever: a meta-analysis
BMC Cardiovascular Disorders, 2005 Background Rheumatic fever continues to put a significant burden on the health of low socio-economic populations in low and middle-income countries despite the near disappearance of the disease in the developed world over the past century.
Volmink Jimmy A +2 more
doaj +1 more source
, 2002 Rheumatic fever is an immunologically mediated inflammatory disease, that occurs as a delayed sequel to group A streptococcal throat infection, in genetically susceptible individuals.
Binotto, Maria Angelica +2 more
core
Acute rheumatic fever in Tunisia. Serotypes of group A streptococci associated with rheumatic fever.
, 1997 International audienceRheumatic fever (RF) is a serious health threat in our country. The annual incidence of cases of acute rheumatic fever (ARF) in 1990 was 30 per 100,000 school-aged children, the prevalence of rheumatic heart diseases (RHD) was 3–6 ...
Kechrid, P +9 more
core +1 more source
Streptococcus and rheumatic fever [PDF]
Current Opinion in Rheumatology, 2012 To give an overview of the current hypotheses of the pathogenesis of rheumatic fever and group A streptococcal autoimmune sequelae of the heart valve and brain.Human monoclonal antibodies (mAbs) derived from rheumatic heart disease have provided evidence for crossreactive autoantibodies that target the dominant group A streptococcal epitope of the ...
openaire +2 more sources