Results 101 to 110 of about 139,089 (353)

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

open access: yesAdvanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang   +13 more
wiley   +1 more source

A predominance of hypertensive heart disease among patients with cardiac disease in Buea, a semi-urban setting, South West Region of Cameroon

open access: yesBMC Research Notes, 2017
Objective The pattern of heart disease is diverse within and among world regions. The little data on the spectrum of heart disease in Cameroon has been so far limited to major cities.
Clovis Nkoke   +6 more
doaj   +1 more source

The great simulator [PDF]

open access: yes, 1993
Cardiac myxoma often simulates multisystem disease and initially defies diagnosis. In this paper, we present three cases of cardiac myxoma in adults.
Aquilina, Oscar   +2 more
core  

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

CURRENT STA TUS OF RHEUMA TIC FEVER AND RHEUMA TIC HEART DISEASE IN NEPAL

open access: yesJournal of Nepal Medical Association, 2003
Rheumatic fever (RF) and rheumatic heart disease (RHD) are common in underdeveloped, deprived and depressed areas of the world. The progression of RHD is rapid in deprived communuties.
Yuba Raj Limbu, A Maskey
doaj   +1 more source

Rheumatic Heart Disease in Asia [PDF]

open access: yesCirculation, 2008
A few years ago, my colleagues and I conducted a systematic review of data relating to the global burden of group A streptococcal diseases.1,2 Population-based data on rheumatic heart disease prevalence from 1985 through 2002 were included. We estimated that there were a minimum of 15.6 million people in the world with rheumatic heart disease, with 282
openaire   +2 more sources

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

open access: yesAdvanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu   +14 more
wiley   +1 more source

Fibrinous Pericardial Effusion and Valvulitis Secondary to Previous Acute Rheumatic Fever: An Unusual Clinical Presentation

open access: yesGüncel Pediatri, 2014
Rheumatic heart disease, a sequela to acute rheumatic fever (ARF), is a major cause of acquired heart disease in children and young adults in developing countries.
Osman Yılmaz   +2 more
doaj   +1 more source

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