Results 101 to 110 of about 184,125 (352)

The burden of rheumatic heart disease among children in Lagos: how are we faring?

The Pan African Medical Journal, 2018
INTRODUCTION: Rheumatic heart disease still remains a cause of morbidity and mortality in low and middle income countries, despite its eradication in developed societies.
Barakat Adeola Animasahun, Akpoembele Deborah Madise Wobo, Adejumoke Yemisi Itiola, Motunrayo Oluwabukola Adekunle, Olusola Yejide Kusimo, Fidelia Bode Thomas   +5 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

CURRENT STA TUS OF RHEUMA TIC FEVER AND RHEUMA TIC HEART DISEASE IN NEPAL

Journal of Nepal Medical Association, 2003
Rheumatic fever (RF) and rheumatic heart disease (RHD) are common in underdeveloped, deprived and depressed areas of the world. The progression of RHD is rapid in deprived communuties.
Yuba Raj Limbu, A Maskey
doaj   +1 more source

Correction:Rheumatic heart disease mortality in Indigenous and non-Indigenous Australians between 2010 and 2017 [PDF]

, 2023

openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

RELATIONSHIP OF TNF-A-308, IL-10–1082 GENE POLYMORPHISMS WITH THE SEVERITY AND SUSCEPTIBILITY OF RHEUMATIC HEART DISEASE IN TURKISH CHILDREN

Российский кардиологический журнал, 2014
Aim. Acute rheumatic fever is an inflammatory disease developing after upper respiratory tract infection with group A streptoccoci and its most important complication is rheumatic heart disease (RHD). Tumor necrosis factor (TNF)-α and interleukin (IL) –1–
Hallioglu Olgu, Balci Sibel, Eras-Erdogan Nazan, Akbas Etem   +3 more
doaj   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Rheumatic Heart Disease Burden

JACC: Advances
Background: Rheumatic heart disease (RHD) is a major challenge to global health, primarily in low- and middle-income countries. Even though RHD is rare in high-income countries, it still poses a health challenge, yet there is a lack of data on its impact
Stefan Milutinovic, MD, Marija Petrovic, MD, PhD, Aya Ziq, MS, Christian Sanchez, BS, Ahmed Sami Hammami, MD, Ricardo Orlando Escarcega, MD, Dustin Begosh-Mayne, MD, Malissa J. Wood, MD, Richard A. Chazal, MD, Juan C. Lopez-Mattei, MD   +9 more
doaj   +1 more source

Vitamin K antagonists remain the INVICTUS standard of care for patients with rheumatic heart disease and atrial fibrillation [PDF]

, 2022
Giovanna Liuzzo, Carlo Patrono
openalex   +1 more source