Results 51 to 60 of about 87,039 (290)

Genetics of rheumatic fever and rheumatic heart disease

Nature Reviews Cardiology, 2019
Rheumatic heart disease (RHD) is a complication of group A streptococcal infection that results from a complex interaction between the genetic make-up of the host, the infection itself and several other environmental factors, largely reflecting poverty.
Karen Sliwa, Tom Parks, Tom Parks, Babu Muhamed   +3 more
openaire   +6 more sources

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

A STUDY ON CARDIOVASCULAR DISEASE PATTERN OF ADMITTED CASES IN NEWLY EMERGED NATIONAL HEART CENTRE

Journal of Nepal Medical Association, 2003
Cardiovascular disease is one of the global leading causes of death . Although in developed countries overall cardiovascular death is declining due to long term decline of rheumatic heart disease (RHD), cerebro vascular and hypertensive heart disease ...
Yuba Raj Limbu, A Maskey, Man Bahadur K.C., R Malla, D Sharma, N K Shrestha   +5 more
doaj   +1 more source

The severe presentation and poor outcomes of rheumatic heart disease in Namibia: Lessons from the REMEDY study

South African Medical Journal, 2023
Background. This paper reports the baseline characteristics and outcomes of 266 Namibian patients in the Global Registry of Rheumatic Heart Disease. Objective.
T Auala, L Zühlke, L Sikwaya, H du Toit, G Karthikeyan, K Teo, S Yusuf, M E Engels, B M Mayosi, C T Hugo-Hamman   +9 more
doaj   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Evaluating the implementation of a dynamic digital application to enable community-based decentralisation of rheumatic heart disease case management in Uganda: protocol for a hybrid type III effectiveness-implementation study

BMJ Open, 2023
Introduction Rheumatic heart disease (RHD) affects over 39 million people worldwide, the majority in low-income and middle-income countries. Secondary antibiotic prophylaxis (SAP), given every 3–4 weeks can improve outcomes, provided more than 80% of ...
Emmy Okello, Craig Sable, David A Watkins, Chris T Longenecker, Jessica Abrams, Andrea Zawacki Beaton, Joselyn Rwebembera, Jenifer Atala, Jafesi Pulle, Rachel Sarnacki, Nicholas Ollberding, Ndate Fall, Yanfang Su, Linda Oyella, Kristen Danforth, Neema W Minja, Sarah R de Loizaga, Jenipher Kamarembo, Francis Odong, Haddy Nalubwama, Doreen Nakagaayi, Judith W Dexheimer   +21 more
doaj   +1 more source

Heart Disease Detection using Quantum Computing and Partitioned Random Forest Methods [PDF]

arXiv, 2022
Heart disease morbidity and mortality rates are increasing, which has a negative impact on public health and the global economy. Early detection of heart disease reduces the incidence of heart mortality and morbidity. Recent research has utilized quantum computing methods to predict heart disease with more than 5 qubits and are computationally ...
arxiv  

Rheumatic Diseases and Heart

, 2023
Rheumatic diseases are generally examined in three different classes; joint diseases, autoimmune connective tissue diseases, and vasculitides. They progress with significant cardiac involvement in all three groups. Cardiac involvement may present in a spectrum ranging from asymptomatic, mild, or subclinical to serious disease with a risk of mortality ...
Küçüker, Serhat, Pamukcu, Melih
openaire   +2 more sources

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening

Advanced Materials Technologies, EarlyView.
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló, Pooya Azizian, Blanca del Pozo, Marta Olle‐Monge, Lourdes Gombau, Joan M. Cabot   +5 more
wiley   +1 more source