Results 281 to 290 of about 1,164,546 (387)

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

open access: yesAdvanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An   +8 more
wiley   +1 more source

microRNAs as Biomarkers and Therapeutic Targets in Rheumatoid Arthritis. [PDF]

open access: yesInt J Mol Sci
Machaj F   +5 more
europepmc   +1 more source

Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group.

open access: yesNew England Journal of Medicine, 2000
eter   +28 more
semanticscholar   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

open access: yesAdvanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu   +5 more
wiley   +1 more source

Rheumatoid arthritis and cardiovascular disease associations in the UK Biobank. [PDF]

open access: yesBMC Med
Salatzki J   +12 more
europepmc   +1 more source

Exploring candidate biomarkers for rheumatoid arthritis through cardiovascular and cardiometabolic serum proteome profiling [PDF]

open access: gold
L. Cuesta-López   +19 more
openalex   +1 more source

Cell Contractile Force‐Mediated Morphogenetic Tissue Engineering via 4D Printed Degradable Hydrogel Scaffolds

open access: yesAdvanced Science, EarlyView.
Through the actuation of cell contractile forces, geometrically complex structures are formed via a bioprinted, rapidly degrading cell‐laden hydrogel system, resulting in cell‐only condensation within a few days of culture. This system supports stem cell differentiation down different lineages and new tissue formation, such as chondrogenesis and ...
Aixiang Ding   +4 more
wiley   +1 more source

Methotrexate mechanism in treatment of rheumatoid arthritis.

open access: yesJoint, bone, spine : revue du rhumatisme, 2019
Benjamin Friedman, B. Cronstein
semanticscholar   +1 more source

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