Results 21 to 30 of about 564,952 (147)

Non-TNF inhibitor switchers versus TNF inhibitor cyclers from multicentre rheumatoid arthritis ultrasonography prospective cohort in Japan

open access: yesImmunological Medicine, 2020
To compare therapeutic efficacy of tumour necrosis factor inhibitor (TNFi) cyclers and non-TNFi switchers in patients with rheumatoid arthritis (RA) having inadequate response to previous TNFis (TNF-IR patients) using composite measures including imaging
Yushiro Endo   +28 more
doaj   +1 more source

Clinical analyses of ultrasound-guided nerve block in lower-extremity surgery: A retrospective study

open access: yesJournal of Orthopaedic Surgery, 2021
Purpose: The purpose of this study is to examine the clinical effects and results of lower-extremity surgery under ultrasound-guided nerve block; time required for nerve block, anesthesia onset time, duration of anesthesia, duration of analgesia ...
Chan Kang   +7 more
doaj   +1 more source

Translational research in rheumatoid arthritis: Exploiting melanocortin receptors [PDF]

open access: yes, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorRheumatoid arthritis (RA) is a chronic inflammatory disease affecting 1% of the ...
Ahmed, Tazeen Jahan
core   +4 more sources

Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis

open access: yesSTAR Protocols, 2022
Summary: By their capacity to induce peripheral T cell tolerance, dendritic cells (DCs) present a promising target cell and therapeutic strategy for treatment of several autoimmune diseases including multiple sclerosis (MS).
Andrea Vogel   +3 more
doaj   +1 more source

Downregulation of Tumour Necrosis Factor α Gene Expression in Peripheral Blood Mononuclear Cells Cultured in the Presence of Tofacitinib Prior to Therapy Is Associated with Clinical Remission in Patients with Rheumatoid Arthritis

open access: yesCurrent Issues in Molecular Biology, 2022
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by pain, synovial hyperplasia, mononuclear cell infiltration, bone erosion and joint destruction.
Elena V. Tchetina   +3 more
doaj   +1 more source

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]

open access: yes, 2007
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Klareskog, Lars   +25 more
core   +1 more source

Influence of Preoperative Physical Function on Gait 1 Month After Total Knee Arthroplasty

open access: yesAnnals of Geriatric Medicine and Research, 2017
Background : This study aimed to identify the preoperative physical performance factors that predict gait speed and endurance 1 month after total knee arthroplasty (TKA).
So Young Lee   +5 more
doaj   +1 more source

The risk of malignancy and its incidence in early rheumatoid arthritis patients treated with biologic DMARDs

open access: yesArthritis Research & Therapy, 2017
Background Treatment with disease-modifying anti-rheumatic drugs (DMARDs) has raised concerns about the risk of malignancies in rheumatoid arthritis (RA) patients.
Soo-Kyung Cho   +4 more
doaj   +1 more source

Author Correction: Associations between hand function and electrophysiological measurements in hand osteoarthritis patients of different ages with or without carpal tunnel syndrome

open access: yesScientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Young Hoon Kim   +5 more
doaj   +1 more source

Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib

open access: yesLife, 2021
We investigated the importance of the baseline expression of genes involved in energy generation, as prognostic biomarkers of the treatment response to tofacitinib in patients with rheumatoid arthritis (RA). Peripheral blood samples were obtained from 28
Elena V. Tchetina   +4 more
doaj   +1 more source

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