Results 41 to 50 of about 622,390 (297)

Evaluation of central corneal thickness and corneal curvature in patients with rheumatoid arthritis

Asian Journal of Medical Sciences, 2022
Background: Rheumatoid arthritis is an autoimmune disease. It is a chronic disease that causes symmetrical deforming type of polyarthritis. Rheumatoid arthritis most commonly involves the anterior segment of the eye. It causes keratoconjunctivitis sicca,
Rubina Huda , Syed Ali Nasar Waris , Sankar Kumar T , Panchapakesa Rajendran C   +3 more
doaj   +1 more source

Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes. [PDF]

, 2017
ObjectiveTo determine whether differentially methylated CpGs in synovium-derived fibroblast-like synoviocytes (FLS) of patients with rheumatoid arthritis (RA) were also differentially methylated in RA peripheral blood (PB) samples.MethodsFor this study ...
Barcellos, Lisa F, Cole, Michael, Criswell, Lindsey A, Firestein, Gary S, Graf, John, Halperin, Eran, Harrison, Ruby, Holingue, Calliope, Link, Thomas, Quach, Diana, Quach, Hong L, Rahmani, Elior, Rhead, Brooke, Shah, Khooshbu, Shao, Xiaorong, Sinclair, Elizabeth, Wang, Wei   +16 more
core   +1 more source

Provision of foot health services for people with rheumatoid arthritis in New South Wales: a web-based survey of local podiatrists [PDF]

, 2013
Background: It is unclear if podiatric foot care for people with rheumatoid arthritis (RA) in New South Wales (NSW) meets current clinical recommendations. The objective of this study was to survey podiatrists' perceptions of the nature of podiatric foot
A Blake, A Williams, AC Redmond, AE Williams, AE Williams, AE Williams, AF Marsman, Arthritis and Musculoskeletal Alliance, AS Graham, CJ Bowen, CM Sofka, DE Turner, DE Turner, GJ Hendry, GJ Hendry, Gordon J Hendry, J Firth, J Michelson, J Woodburn, Joshua Burns, JS Smolen, K Hennessy, K Rome, K Rome, Kathryn A Gibson, Keith Rome, Kevin Pile, KL Manfreda, Luke Taylor, M van der Leeden, M van der Leeden, MA D'Agostino, MR Backhouse, National Collaborating Centre for Chronic Conditions, O Wilson, P Helliwell, Podiatry Rheumatic Care Association, R Luqmani, RJ Wakefield, SIG Network, SM Bergin, The Royal College of General Practitioners, Verona du Toit, W Fan   +43 more
core   +2 more sources

Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]

, 2019
Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio, Di Franco, Manuela, Guzzo, Maria Paola, Iannuccelli, Cristina, Lucchino, Bruno, Spinelli, Francesca Romani   +5 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis

Frontiers in Immunology, 2018
ObjectiveDendritic cells (DCs) are key orchestrators of immune function. To date, rheumatoid arthritis (RA) researchers have predominantly focused on a potential pathogenic role for CD1c+ DCs.
Faye A. H. Cooles, Faye A. H. Cooles, Amy E. Anderson, Amy E. Anderson, Andrew Skelton, Andrew Skelton, Arthur G. Pratt, Arthur G. Pratt, Mariola S. Kurowska-Stolarska, Mariola S. Kurowska-Stolarska, Iain McInnes, Iain McInnes, Catharien M. U. Hilkens, Catharien M. U. Hilkens, John D. Isaacs, John D. Isaacs   +15 more
doaj   +1 more source

Systematic review of the psychometric properties of patient-reported outcome measures for foot and ankle in rheumatoid arthritis [PDF]

, 2019
Background Foot problems and pain are common in patients with rheumatoid arthritis. Patient-reported outcome measures provide a standardized method of capturing patients’ perspectives of their functional status and wellbeing.
Cervera Garvi, Pablo, Gijón-Noguerón, Gabriel, Nester, Christopher J., Ortega-Avila, Ana Belen, Ramos Petersen, Laura   +4 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Treating Rheumatoid Arthritis yesterday and today [PDF]

, 2004
Rheumatoid arthritis is a chronic, systemic inflammatory disorder that mainly affects joints. It is the most common form of inflammatory joint disease, and the second commonest joint disease, osteoarthritis being the commonest.
Mallia, Carmel
core  

Synovial tissue macrophages: friend or foe? [PDF]

, 2017
Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce ...
Alivernini, Stefano, Kurowska-Stolarska, Mariola   +1 more
core   +2 more sources