Results 31 to 40 of about 622,390 (297)

NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease

Acta Biochimica et Biophysica Sinica, 2022
The NLRP3 inflammasome is a multiprotein binding compound comprising NLRP3, connector protein ASC, and effector protein pro-caspase-1. When the NLRP3 inflammasome senses a danger signal from the host or pathogen, activated caspase-1 cleaves the ...
Guan Yanling, Gu Yiyue, Li Hao, Liang Bo, Han Chenchen, Zhang Yu, Liu Qian, Wei Wei, Ma Yang   +8 more
doaj   +1 more source

Symptom complexes in patients with seropositive arthralgia and in patients newly diagnosed with rheumatoid arthritis: a qualitative exploration of symptom development [PDF]

, 2014
Objective: The aim of this study was to explore symptoms and symptom development during the earliest phases of rheumatoid arthritis (RA) in patients with seropositive arthralgia and patients newly diagnosed with ...
Aletaha, B. Maat, C. D. Mallen, D. van Schaardenburg, Finckh, Hyrich, K. Raza, L. A. van de Stadt, L. H. D. van Tuyl, M. Sloots, Mays, Nielen, Nielen, R. J. Stack, R. Tiwana, Rantap    -Dahlqvist, Suter, van der Helm-Vanmil, van der Linden, van der Linden, W. Hoogland   +20 more
core   +1 more source

Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases [PDF]

, 2016
Antibodies against carbamylated proteins (anti-CarP) have been recently identified in the sera of patients with rheumatoid arthritis (RA). The objective of the study was to evaluate the prevalence, sensitivity and specificity of anti-CarP compared to ...
Alessandri, Cristiano, Barbati, Cristiana, Ceccarelli, Fulvia, Colasanti, Tania, Conti, Fabrizio, DI FRANCO, Manuela, Mancini, Riccardo, Morello, Francesca, Pecani, Arbi, Pendolino, Monica, Priori, Roberta, Riccieri, Valeria, Sabatinelli, Danilo, Spinelli, FRANCESCA ROMANA, Truglia, Simona, Valesini, Guido, Vomero, Marta   +16 more
core   +1 more source

Establishment of a qualified integrated care system after total knee arthroplasty as a role of regional rheumatoid and degenerative arthritis centers

BMC Geriatrics, 2022
Background The geriatric population and advanced knee osteoarthritis are rapidly increasing in Korea, and the socioeconomic burden of total knee arthroplasty (TKA) is increasing.
Eun Young Han, Sang Rim Kim, Kye Hee Cho, Sang Hee Im   +3 more
doaj   +1 more source

Myocardial infarction and mortality following joint surgery in patients with rheumatoid arthritis: a retrospective cohort study [PDF]

, 2016
Summary of patient level comparing those with rheumatoid arthritis to those without rheumatoid arthritis.
Caroline A. Brand, Joanne Tropea, Megan Bohensky, Sharon Van Doornum   +3 more
core   +5 more sources

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Effectiveness of self-management interventions in inflammatory arthritis: a systematic review informing the 2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis

RMD Open, 2021
Objective To perform a systematic review (SR) on the effectiveness of self-management interventions, in order to inform the European League Against Rheumatism Recommendations for its implementation in patients with inflammatory arthritis (IA).Methods The
Andréa Marques, Ailsa Bosworth, Eduardo Santos   +2 more
doaj   +1 more source

‘The current mental health status of children and young people with JIA, and their wider family’: a charity partner collaboration survey

Pediatric Rheumatology Online Journal, 2023
Background This paper presents insight into the scale of mental health concerns for families who have a child or young person with a diagnosis of Juvenile Idiopathic Arthritis (JIA) living in any of the four nations of the United Kingdom (UK).
Polly Livermore, S. Ainsworth, R. Beesley, S. Douglas, E. Earle, D. Wilson, L. Woolley, J. Clinch   +7 more
doaj   +1 more source

Change in bone mineral density in post menopausal women with rheumatoid arthritis [PDF]

, 2013
Introduction: Low bone mass is a serious complication of post menopausal women with rheumatoid arthritis. We determined the Change in Bone Mineral Density in postmenopausal women with rheumatoid arthritis.
Aghaei, M., Aili, A., Jamshir, M., Khani, S.H., Mohebi, E.G., Pour, N.B., Sedighi, S., Shirashiani, M., Shojaa, M., Zayeni, H.   +9 more
core   +1 more source

Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways

Frontiers in Immunology, 2019
Class 1 Phosphoinositide-3-Kinases (PI3Ks) have been widely studied and mediate essential roles in cellular proliferation, chemotaxis, insulin sensitivity, and immunity.
Omar Sharif, Omar Sharif, Julia Stefanie Brunner, Julia Stefanie Brunner, Andrea Vogel, Andrea Vogel, Gernot Schabbauer, Gernot Schabbauer   +7 more
doaj   +1 more source