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Rheumatoid Factor

Rheumatic Disease Clinics of North America, 1987
Many human RF-associated crossreactive idiotypes (CRIs) have been defined. Since these CRIs probably are the phenotypic markers of Ig variable region genes, the data suggest that human RFs employ several Ig variable region genes which are common among outbred human populations.
P P, Chen, S, Fong, D A, Carson
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Rheumatoid factors

Clinical Biochemistry, 1993
Rheumatoid factors (RFs) have been studied for over 50 years and are probably the most written about of any antibody. Nevertheless, the etiology of these RFs and the precise role they play in the pathogenesis of rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) remain a major interest.
T L, Moore, R W, Dorner
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Rheumatoid Factors and Rheumatoid Arthritis

Scandinavian Journal of Rheumatology, 1988
Rheumatoid factors (RFs) are autoantibodies which bind the Fc region of IgG (1, 2). They can be induced in experimental animals by B cell mitogens and by immunization with a variety of different an...
K, Aho   +3 more
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Imipramine, rheumatoid arthritis and rheumatoid factor

Current Medical Research and Opinion, 1977
SummaryA double-blind placebo-controlled trial was carried out in 20 patients with classical rheumatoid arthritis to study the effect of imipramine on rheumatoid factor titres. Patients were allocated at random to receive 6-weeks treatment with imipramine, in low dosage, or placebo in addition to their antirheumatic medication.
P D, Fowler   +4 more
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Rheumatoid factors in rheumatoid arthritis and vasculitis

Rheumatology International, 1985
To study the occurrence of rheumatoid factors (RF) in relation to the activity of rheumatoid arthritis and the occurrence of vasculitis, RF of IgM, IgA, and IgG classes were measured in sera from 35 patients with definite or classic rheumatoid arthritis (RA) using ELISA.
M L, Westedt   +7 more
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Purification of the rheumatoid factor

Clinica Chimica Acta, 1964
Abstract A preparation of rheumatoid factor was obtained from a pooled rheumatoid serum by absorption to diphtheria toxoid-human antitoxin precipitate, subsequent elution by lowering the pH, and gel nitration of the eluent. The isolated rheumatoid factor was homogeneous in the analytical ultracentrifuge and in immunoelectropho-resis.
K, SIMONS   +3 more
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The rheumatoid factors

Journal of Chronic Diseases, 1963
GENERAL reviews of rheumatoid arthritis serology summarized knowledge as of 1957 and 1959 [l, 21. The Current Status of the Rheumutoid Factor was the title of a publication appearing early in 1962 [3]. It is the author’s aim to emphasize developments of the past 3 years within the framework of a limited general review.
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Rheumatoid factor in syphilis

Journal of Clinical Microbiology, 1985
Immunoglobulin M (IgM) antibodies directed against IgG antibodies (rheumatoid factor [RF]) are known to occur often in patients with syphilis and to interfere with serological tests measuring specific antibodies of the IgM class. In this study we examined the occurrence and specificity of the RF and demonstrated a simple method to detect and eliminate ...
E H, Cerny   +3 more
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Pseudoglobulin Rheumatoid Factors

The Journal of Immunology, 1965
Summary Although the rheumatoid factors (RF) are believed to be relatively insoluble in dilute salt solutions, considerable RF activity in pseudoglobulin fractions was encountered on examination of certain sera of persons having rheumatoid arthritis.
R, HEIMER, C J, NOSENZO
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Rheumatoid factor revisited

Current Opinion in Rheumatology, 2004
Initial studies of the pathogenesis of rheumatoid arthritis focused on the role of rheumatoid factor and immune complex-associated vasculitis and synovitis. Subsequent work has delineated T cell responses, the role of cytokines, chemokines, and the aggressive nature of rheumatoid synovitis.
Thomas, Dörner   +3 more
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