Results 241 to 250 of about 400,814 (315)

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda, Momo Uchizawa, Chihiro Terasaka, Takumi Abe, Tetsuro Nakamura, Yuka Nishibata, Yusho Ueda, Daigo Nakazawa, Utano Tomaru, Akihiro Ishizu   +9 more
wiley   +1 more source

Consensus statements on the transition care for adolescents with rheumatic diseases in Saudi Arabia. [PDF]

Ther Adv Musculoskelet Dis
Nashawi M, Alahmari H, Basahl E, Alsulaim T, Alhamed A, Mirza A, Hafiz W, Mukhtar D, Aljaser A, Rayes HA, Albader H, Alqanatish J, Alsufyani K, Alderaan K, Majeed M, Somaily M, Altowijry M, Attar M, Olfat M, Omair MA, Alessi M, Al-Mayouf SM, Alzahrani Z, Al Ghanim N, Almutairi A, Alsuwairi W.   +25 more
europepmc   +1 more source

Romosozumab-Associated Recurrent Erythema Nodosum in Mixed Connective Tissue Disease. [PDF]

ACR Open Rheumatol
Diaz Macip JL, Turcu I, Goranti J, Sivaguru S, Kodam SP, Afzal Z.   +5 more
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Rheumatoid arthritis and interstitial lung disease: the role of comorbidities-a retrospective analysis of two RA inception cohorts in the UK. [PDF]

Rheumatology (Oxford)
Dacheva R, Busby A, Kiely P, Young A, Walsh DA, McWilliams DF, Galloway J, Nikiphorou E.   +7 more
europepmc   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

ACR Presidential Address: The American College of Rheumatology in 2025 - The Strength, Resilience, and Importance of Our Rheumatology Community. [PDF]

Arthritis Rheumatol
Langford CA.
europepmc   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Real-world effectiveness, safety and patient-reported outcomes of sarilumab in patients with rheumatoid arthritis: a 52-week, prospective, open-label, non-interventional, observational, nationwide, large-cohort study in Japan (PROFILE-J). [PDF]

RMD Open
Tanaka Y, Hanami K, Miyazaki Y, Ishigatsubo Y, Iwamoto T, Ushio K, Okano Y, Onobori M, Kawahata K, Saegusa J, Nakamura Y, Natsumeda M, Nozaki Y, Miyamoto T, Yamanishi Y, Ishiguro N, Kumanogoh A, Takeuchi T, Tohma S, Fujino Y, Kameda H.   +20 more
europepmc   +1 more source

Differences in Self-Reported Medication Nonadherence and Its Drivers in Young Adults Versus Older Adults With Systemic Lupus Erythematosus. [PDF]

J Rheumatol
Concannon HR, Sun K, Rogers JL, Clowse MEB, Randell RL, Maheswaranathan M, Criscione-Schreiber LG, Harris NJ, Eudy AM, Sadun RE.   +9 more
europepmc   +1 more source