Results 251 to 260 of about 400,814 (315)

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source

Clinical significance of erythrocyte sedimentation rate-based stratification in a large retrospective SLE cohort. [PDF]

Front Immunol
Wang F, Xu Y, Zhang W, Pan W, Liu L, Wu M, Ding F, Hu H, Ding X, Wei H, Zou Y, Kong W, Zhu Y, Feng X, Sun L.   +14 more
europepmc   +1 more source

Nationwide Temporal Trends in Adverse Pregnancy Outcomes and Treatments in Systemic Lupus Erythematosus Pregnancy Over Two Decades in Sweden

Arthritis &Rheumatology, EarlyView.
Objective This nationwide descriptive study examined temporal trends in adverse pregnancy outcomes (APOs) and treatments in systemic lupus erythematosus (SLE) pregnancies in Sweden over 2003 to 2022. Methods Using nationwide Swedish registers, we identified 1,417 pregnancies of women with prevalent SLE and delivery dates in 2003 to 2022 and matched ...
Ngoc V. Nguyen, Anna Sandström, Annica Dominicus, Elisabet Svenungsson, Karin Hellgren, Julia F. Simard, Elizabeth V. Arkema   +6 more
wiley   +1 more source

Comment on: "Sirolimus versus mycophenolate mofetil for the treatment of lupus nephritis: Results from a real-world CSTAR cohort study". [PDF]

Rheumatol Immunol Res
Bakay U.
europepmc   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Pulmonary nodules in chronic nonbacterial osteomyelitis-the importance of considering histoplasmosis in endemic regions: comment on the article by Hospach et al. [PDF]

ACR Open Rheumatol
Rodrigues Campos L, Brüzzi Porto LF, Niskier Cukier F, do Prado Juca Filho G, Martins Costa F, Roberto Sztajnbok F, Rodrigues Fonseca A.   +6 more
europepmc   +1 more source

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Accuracy of Visual Inspection Alone to Assess Joint Effusions of the Hand: Cross-Sectional Study.

J Med Internet Res
Ye C, Mitchell JR, Al-Matar S, Bishay M, Jones N, Sholter D, Johnson D, Katz S, Russell AS, Abdalla M.   +9 more
europepmc   +1 more source

Expert collaborative evidence-based consensus for childhood lupus nephritis diagnosis and treatment: unifying clinical approach in Saudi Arabia. [PDF]

Pediatr Rheumatol Online J
AlMutairi A, Bahassan A, Sandokji I, Basahl E, Al-Mayouf SM, Alhasan K, Alsaran K, Majeed M, Kari JA, AlSuwairi W, AlAnazi A, Alenazi A, Abdulmajeed N, AlMutairi S, AlMaiman W, Olfat M, AlTuwigri M, Alabdulqader M, Asiri A, Hakami A, AlSufyani K, AlMokali K, AlThagafi H, Al Alsheikh K, Anam E, Zahran S, Al Rayes H, Ankawi G, Nashawi M.   +28 more
europepmc   +1 more source