Results 181 to 190 of about 156,275 (343)

IFNγ Signaling Impairs Regulatory B Cell Function Resulting in Worse Control of Esophageal Food Allergy

Allergy, EarlyView.
We used patient samples and a murine model to understand the contribution of Bregs to EoE immunopathology. We find that Breg‐derived IL‐10 is important for controlling EoE, but that Breg expansion and function are impaired in this condition. We identify IFNγ as a key negative regulator of Breg function in mice and patients with EoE. Bregs, regulatory B
Rachel L. Clement, Julie Dilollo, Eric M. Rodríguez‐López, Cleandre M. Guerrier, David A. Hill   +4 more
wiley   +1 more source

Fungal Diversity and Interactions in the Nasal and Oral Cavities of Individuals with Allergic Rhinitis, Asthma and Healthy Controls. [PDF]

Microorganisms
Pérez-Losada M.
europepmc   +1 more source

SCIT With Hypoallergenic Bet v 1 Compared to Conventional Extract: Poorer Blocking Antibody Capacity Dominated by IgG1 Instead of IgG4

Allergy, EarlyView.
A 6‐month randomized, double‐blind, placebo‐controlled first‐in‐human clinical trial was conducted in birch pollen allergic patients comparing the Bet v 1‐fold‐variant BM41 with a licensed birch pollen extract‐based treatment, as active comparator, and placebo.
Lorenz Aglas, Line Kring Tannert, Serge A. Versteeg, Scott A. Smith, Ewa A. Bartko, Mario Wenger, Amin Kraiem, Hannah Widauer, Natália Nunes, Sibile Sinkunaite, Frank Stolz, Laurian Jongejan, Angela Neubauer, Lars H. Blom, Fatima Ferreira, Lars K. Poulsen, Carsten Bindslev‐Jensen, Ronald van Ree   +17 more
wiley   +1 more source

Association between gut microbiota and allergic rhinitis: a systematic review and meta-analysis. [PDF]

PeerJ
Li M, Wang Q, Wang R, Pu J, Zhang Y, Ye S, Liang J, Li T, Gu Q.   +8 more
europepmc   +1 more source

The Epidemiology of Chronic Urticaria in Cape Town, South Africa: A Review of Two Tertiary Referral Centers

Allergy, EarlyView.
Cascia Day, Mimi Deetlefs, Lovemore Mapahla, Yejin Jang, Qiqa Gusha‐Mhlekude, Sicelo Ntuli, Balican Hlungwani, Susanna Kannenberg, Emma Kruger, Ndapewa Ambondo, Willem Visser, Thuraya Isaacs, Rannakoe Lehloenya, Jonny Peter   +13 more
wiley   +1 more source

Basophil Activation Test: Bridging Allergy and Oncology for Diagnostic, Therapeutic and Prognostic Applications in AllergoOncology: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal, Jitesh Chauhan, Edward Knol, Rodolfo Bianchini, Mariana Castells, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Christoph Bergmann, Sophia N. Karagiannis, Heather J. Bax   +18 more
wiley   +1 more source

Is Allergic Rhinitis Related to Otitis Media with Effusion in Adults and Children? Applying Epidemiological Guidelines for Causation. [PDF]

Cells
Vlastos IM, Tsotsiou N, Almomani M, Doulaptsi M, Karatzanis A, Prokopakis E.   +5 more
europepmc   +1 more source

Mepolizumab Effectiveness in Severe Asthma With/Without Chronic Rhinosinusitis With Nasal Polyps: Real‐World Pooled Analysis

Allergy, EarlyView.
MEPOLYP was a pooled analysis of 1037 patients with SAEP[±]CRSwNP. Mepolizumab was associated with a reduction in CSEs, OCS use, and BEC, and improved lung function and ACT score. Over 47% of patients fulfilled ≥ 3 clinical remission criteria. When compared, there was a 30.0% incremental benefit of mepolizumab in reducing CSEs for patients with SAEP ...
Florence Schleich, Stelios Loukides, Rekha Chaudhuri, Joerg D. Leuppi, Enrico Heffler, Cristian Domingo, Claudio Micheletto, Thomas Paulsson, Nina Gaw, Konstantina Kallinikou, Carla Vossen, Florent Guelfucci, Jyothi Menon, Armel Ngami, Ines Palomares   +14 more
wiley   +1 more source

Recent Studies and Prospects of Biologics in Allergic Rhinitis Treatment. [PDF]

Int J Mol Sci
Cheng X, Zhou Y, Hao Y, Long Z, Hu Q, Huo B, Xie T, Chen S, Zhou L, Zhou T, Li L, Cheng Q, Chen J.   +12 more
europepmc   +1 more source

A Growing Concern for Cashew and an Unexpected Risk From Almonds: Data From the Anaphylaxis Registry

Allergy, EarlyView.
Tree nut‐induced anaphylaxis constitutes 23% of food‐induced anaphylaxis among the anaphylaxis registry. Confirmed elicitors differed between children (n = 845) and adults (n = 238): cashew, hazelnut, and walnut were most frequent among children, while hazelnut, walnut, and almond were most frequent among adults.
Veronika Höfer, Sabine Dölle‐Bierke, Dominique Sabouraud‐Leclerc, Amandine Divaret‐Chauveau, Alice Köhli, Maria Breiding, Karin Hartmann, Lars Lange, Nikolaos Papadopoulos, Hagen Ott, Stephanie Hompes, Maria Beatrice Bilò, Blanca E. García, Margitta Worm   +13 more
wiley   +1 more source