Results 201 to 210 of about 89,228 (352)

THE PATTERN OF HEARING LOSS AS SEEN AT THE UNIVERSITY OF BENIN TEACHING HOSPITAL, BENIN CITY, NIGERIA

open access: yesGomal Journal of Medical Sciences, 2014
Background: Hearing loss is a major cause of disability in developing countries. It presents with enormous problems in Nigeria. The objectives of this study were to determine the gender and age distribution, types, severity and the aetiological factors
Paul Roosvelt Oserhemhen Chukwuemeka Adobamen
doaj  

Periostin as a marker of mucosal remodelling in chronic rhinosinusitis

open access: bronze, 2017
J.A. Ebenezer   +9 more
openalex   +2 more sources

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

open access: yesAllergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh   +7 more
wiley   +1 more source

Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis.

open access: yesJournal of Allergy and Clinical Immunology: In Practice, 2019
W. Stevens   +12 more
semanticscholar   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

open access: yesAllergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm   +9 more
wiley   +1 more source

Early and Sustained Asthma Control and Remission in Real‐World Patients With Severe Eosinophilic Asthma Treated With Benralizumab: XALOC‐2

open access: yesClinical &Experimental Allergy, EarlyView.
Real‐world patients with severe eosinophilic asthma treated with benralizumab showed early and sustained improvements in symptoms. Clinically meaningful improvements began as early as one week after benralizumab initiation, regardless of previous biologic use, and further improved over the following year.
Erika Penz   +12 more
wiley   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

open access: yesClinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna   +10 more
wiley   +1 more source

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