Results 201 to 210 of about 89,228 (352)
Background: Hearing loss is a major cause of disability in developing countries. It presents with enormous problems in Nigeria. The objectives of this study were to determine the gender and age distribution, types, severity and the aetiological factors
Paul Roosvelt Oserhemhen Chukwuemeka Adobamen
doaj
Periostin as a marker of mucosal remodelling in chronic rhinosinusitis
J.A. Ebenezer +9 more
openalex +2 more sources
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis.
W. Stevens +12 more
semanticscholar +1 more source
Getting involved in ENT clinical research in the UK; how can the NIHR Clinical Research Network help? [PDF]
Bhutta, Mahmood +3 more
core +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
Editorial: Recent advances in rhinology 2024. [PDF]
Conti DM, Scadding GK.
europepmc +1 more source
Real‐world patients with severe eosinophilic asthma treated with benralizumab showed early and sustained improvements in symptoms. Clinically meaningful improvements began as early as one week after benralizumab initiation, regardless of previous biologic use, and further improved over the following year.
Erika Penz +12 more
wiley +1 more source
Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna +10 more
wiley +1 more source

