Results 31 to 40 of about 46,812 (255)

Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPD

Frontiers in Immunology, 2020
Respiratory viral infections, particularly those caused by rhinovirus, exacerbate chronic respiratory inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD).
P. Veerati, N. Troy, A. Reid, Ngan Fung Li, K. Nichol, P. Kaur, S. Maltby, P. Wark, D. Knight, A. Bosco, C. Grainge, N. Bartlett   +11 more
semanticscholar   +1 more source

Pneumonia Caused by Rhinovirus [PDF]

Clinical Infectious Diseases, 2000
Rhinovirus infections, although usually limited to the upper respiratory tract, can extend beyond the oropharynx and may cause complications in the lower respiratory tract, including pneumonia [1‐3]. We describe a case of rhinovirus pneumonia in an infant boy in which rhinovirus was recovered from the lung and analysis of hyperimmune serum to the ...
Masami Imakita, Kimiyasu Shiraki, Chikao Yutani, Hatsue Ishibashi-Ueda   +3 more
openaire   +3 more sources

Rhinovirus infections [PDF]

Postgraduate Medical Journal, 1973
Summary One hundred and seventy-five rhinoviruses were isolated from 4·4% of patients in the general practice survey and 44 from 1·8% of children in the hospital survey. Isolations were made at all times of the year and although isolated most frequently from cases of common cold rhinoviruses were also found in association with other ...
openaire   +2 more sources

Mechanisms of Rhinovirus Neutralisation by Antibodies [PDF]

Viruses, 2021
Antibodies are a critical immune correlate of protection for rhinoviruses, particularly those antibodies found in the secretory compartment. For nonenveloped viruses such as rhinoviruses, antibody binding to regions of the icosahedral capsid can neutralise infections by a number of different mechanisms.
Lila Touabi, Faryal Aflatouni, Gary R. McLean, Gary R. McLean   +3 more
openaire   +4 more sources

Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP. [PDF]

PLoS ONE, 2017
Bronchial epithelial cells (BEC) are primary target for Rhinovirus infection through attaching to cell membrane proteins. OM-85, a bacterial extract, improves recovery of asthma and COPD patients after viral infections, but only part of the mechanism was
Michael Roth, Christian Pasquali, Daiana Stolz, Michael Tamm   +3 more
doaj   +1 more source

Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features

Clinical and Translational Allergy, 2012
Background Human rhinoviruses, major precipitants of asthma exacerbations, induce lower airway inflammation and mediate angiogenesis. The purpose of this study was to assess the possibility that rhinoviruses may also contribute to the fibrotic component ...
Skevaki Chrysanthi L, Psarras Stelios, Volonaki Eleni, Pratsinis Harris, Spyridaki Irini S, Gaga Mina, Georgiou Vassiliki, Vittorakis Stylianos, Telcian Aurica G, Maggina Paraskevi, Kletsas Dimitris, Gourgiotis Dimitrios, Johnston Sebastian L, Papadopoulos Nikolaos G   +13 more
doaj   +1 more source

Rhinovirus and Innate Immune Function of Airway Epithelium

Frontiers in Cellular and Infection Microbiology, 2020
Airway epithelial cells, which lines the respiratory mucosa is in direct contact with the environment. Airway epithelial cells are the primary target for rhinovirus and other inhaled pathogens. In response to rhinovirus infection, airway epithelial cells
H. Ganjian, C. Rajput, M. Elzoheiry, U. Sajjan   +3 more
semanticscholar   +1 more source

Respiratory infections in children and adolescents in Germany during the COVID-19 pandemic [PDF]

Journal of Health Monitoring, 2023
Background: Before the COVID-19 pandemic, acute respiratory infections (ARIs) in children were mainly characterised by three pathogens: respiratory syncytial viruses (RSV), influenza viruses and rhinoviruses.
Udo Buchholz, Ann-Sophie Lehfeld, Kristin Tolksdorf, Wei Cai, Janine Reiche, Barbara Biere, Ralf Dürrwald, Silke Buda   +7 more
doaj   +1 more source

Rhinovirus and the initiation of asthma [PDF]

Current Opinion in Allergy & Clinical Immunology, 2009
Virus-induced wheezing in infancy is a risk factor for asthma, and recent studies have highlighted the role of rhinoviruses in causing acute illnesses and as a possible contributing factor to chronic asthma.Human rhinoviruses (HRVs) have long been known as the most common cause of common cold in infants and children.
openaire   +3 more sources

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

PLoS Pathogens, 2010
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial ...
Louise Slater, Nathan W Bartlett, Jennifer J Haas, Jie Zhu, Simon D Message, Ross P Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L Clarke, Maria G Belvisi, Onn M Kon, Takashi Fujita, Peter K Jeffery, Sebastian L Johnston, Michael R Edwards   +14 more
doaj   +1 more source