Results 31 to 40 of about 31,404 (177)
Rhinovirus and the initiation of asthma [PDF]
Virus-induced wheezing in infancy is a risk factor for asthma, and recent studies have highlighted the role of rhinoviruses in causing acute illnesses and as a possible contributing factor to chronic asthma.Human rhinoviruses (HRVs) have long been known as the most common cause of common cold in infants and children.
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Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication
Evidence exists that the typically antiviral signaling mediator STING is, counterintuitively, needed for optimal human rhinovirus infection. Here the authors confirm this finding and show how human rhinovirus can reduce stored Ca2+ levels to drive this ...
Martha Triantafilou+11 more
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Human rhinoviruses are the most common respiratory viruses detected in patients after hematopoietic cell transplantation. Although rhinovirus appears to occasionally cause severe lower respiratory tract infection in immunocompromised patients, the ...
Sachiko Seo+11 more
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Incidence and Outcome of Coinfections with SARS-CoV-2 and Rhinovirus
Background: We aimed to compare the clinical severity in patients who were coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and rhinovirus or monoinfected with a single one of these viruses.
Elisabeth Le Glass+14 more
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Defining critical roles for NF‐κB p65 and type I interferon in innate immunity to rhinovirus
The importance of NF‐κB activation and deficient anti‐viral interferon induction in the pathogenesis of rhinovirus‐induced asthma exacerbations is poorly understood.
Nathan W. Bartlett+17 more
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Rhinovirus exacerbates house-dust-mite induced lung disease in adult mice.
Human rhinovirus is a key viral trigger for asthma exacerbations. To date, murine studies investigating rhinovirus-induced exacerbation of allergic airways disease have employed systemic sensitisation/intranasal challenge with ovalbumin.
Jennifer A Phan+6 more
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Acute otitis media (AOM) is one of the most common infectious diseases in pediatric clinical facilities and has a significant impact on health care. It is a polymicrobial disease and is usually preceded by a viral upper respiratory tract infection.
Anton Budhi Darmawan+5 more
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Pathogenesis of rhinovirus infection [PDF]
Since its discovery in 1956, rhinovirus (RV) has been recognized as the most important virus producing the common cold syndrome. Despite its ubiquity, little is known concerning the pathogenesis of RV infections, and some of the research in this area has led to contradictions regarding the molecular and cellular mechanisms of RV-induced illness.
Joshua L. Kennedy+4 more
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Population structure and evolution of Rhinoviruses.
Rhinoviruses, formerly known as Human rhinoviruses, are the most common cause of air-borne upper respiratory tract infections in humans. Rhinoviruses belong to the family Picornaviridae and are divided into three species namely, Rhinovirus A, -B and -C ...
Vaishali P Waman+3 more
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Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses to rhinovirus infection in allergic asthma is unknown.
Nadine Upton+17 more
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