Results 51 to 60 of about 1,791 (156)

Traditional Chinese Medicine for Diabetic Sarcopenia: A Review and Its Related Mechanisms

open access: yesJournal of Diabetes Research, Volume 2026, Issue 1, 2026.
As societies age worldwide, diabetic sarcopenia has become increasingly common. The development of this disorder involves intricate pathophysiological processes, with contributions from multiple mechanisms: insulin resistance, ongoing inflammatory responses, oxidative damage, buildup of advanced glycation end products (AGEs), compromised mitochondrial ...
Zicheng Ye   +4 more
wiley   +1 more source

Zhizhu Kuanzhong, a traditional Chinese medicine, alleviates gastric hypersensitivity and motor dysfunction on a rat model of functional dyspepsia

open access: yesFrontiers in Pharmacology, 2022
Ethnopharmacological relevance: Zhizhu Kuanzhong (ZZKZ) is a traditional Chinese medicine modified from classic formula Zhizhu decoction in “Synopsis of Golden Chamber” (Han Dynasty in the 3rd century) and the Zhizhu pill in “Differentiation on ...
Zhuanglong Xiao   +14 more
doaj   +1 more source

Cytokine Changes With Effective Drug Therapy for Juvenile Myasthenia Gravis

open access: yesJournal of Immunology Research, Volume 2026, Issue 1, 2026.
Objective In order to investigate the therapeutic mechanism of Jianpiyiqi Granule in juvenile myasthenia gravis (JMG) and find the immune‐associated cytokines or signaling pathways targeted by this intervention. Methods (1) We extracted JMG serum samples from the sample bank of the Hebei Provincial Key Laboratory of Myasthenia Gravis before and after ...
Yuanyuan Geng   +6 more
wiley   +1 more source

Systematic review and meta-analysis of Chinese herbal formula Tongxie Yaofang for diarrhea-predominant irritable bowel syndrome: Evidence for clinical practice and future trials

open access: yesFrontiers in Pharmacology, 2022
Introduction: Diarrhea-predominant irritable bowel syndrome (IBS-D) significantly decreases the quality of life of patients and their families, and affects patients’ mental health. No specific western medications are available.
Shi-Bing Liang   +21 more
doaj   +1 more source

Chinese Herbal Medicines for Diabetic Cardio‐Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms

open access: yesJournal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Currently, the global incidence of diabetes is increasing, particularly in populous developing regions. In China, over 290 million people are affected by diabetic cardio‐cerebrovascular diseases. These diseases account for more than 40% of deaths and impose a significant economic burden on both society and families.
Ying Su   +7 more
wiley   +1 more source

Analysis of Chemical Components and Blood‐Absorbed Components in Youjing Granules by UHPLC‐Q‐Orbitrap‐MS

open access: yesAnalytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT This study investigates the chemical components of Youjing Granules (YG) and identifies blood‐absorbed components in rat serum following YG administration via gavage. Chemical components and blood‐absorbed components of YG were analysed and identified using ultra‐high‐performance liquid chromatography coupled with hybrid quadrupole‐orbitrap ...
Mingxin Guo   +5 more
wiley   +1 more source

Quality Analysis of Raw Material and Products of Goat Bezoar (Houzao), a Mysterious Traditional Medicine

open access: yesPhytochemical Analysis, Volume 36, Issue 7, Page 2182-2196, October 2025.
Goat bezoar is a precious imported Chinese Medicine widely used for centuries in pediatric treatments. However, its unclear chemical profile brings challenge for the identification and the establishment of quality standards. In this study, qualitative and quantitative determination methods of goat bezoar chemical profile were well developed and ...
Sing‐Wan Pun   +8 more
wiley   +1 more source

Atractylenolide I Induces Apoptosis and Suppresses Glycolysis by Blocking the JAK2/STAT3 Signaling Pathway in Colorectal Cancer Cells

open access: yesFrontiers in Pharmacology, 2020
Colorectal cancer (CRC) is the third most common cancer worldwide and is associated with a poor clinical outcome and survival. Therefore, the development of novel therapeutic agents for CRC is imperative.
Yanxi Li   +5 more
doaj   +1 more source

Fermented Rhizoma Atractylodis Macrocephalae alleviates high fat diet-induced obesity in association with regulation of intestinal permeability and microbiota in rats [PDF]

open access: yesScientific Reports, 2015
AbstractAccumulating evidence suggests the anti-inflammatory and anti-obesity activities of Rhizoma Atractylodis Macrocephalae (RAM). Here, we evaluated the anti-obesity impact of unfermented (URAM) versus fermented RAM (FRAM) using both in vitro and in vivo models. Both URAM and FRAM exhibited marked anti-inflammatory, anti-adipogenic and anti-obesity
Wang, Jing-Hua   +4 more
openaire   +3 more sources

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

open access: yesCell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su   +5 more
wiley   +1 more source

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