Results 231 to 240 of about 161,350 (264)

Rho exchange factors in the cardiovascular system

Current Opinion in Pharmacology, 2008
Increasing evidence has accumulated to implicate overactivation of Rho protein as a common component for the pathogenesis of several cardiovascular disorders including hypertension, coronary and cerebral vasospasm, atherosclerosis, and diabetes. Recent advances in Rho protein signaling research indicate that the Rho exchange factors (Rho GEFs) which ...
Gervaise, Loirand, Elizabeth, Scalbert, Antoine, Bril, Pierre, Pacaud   +3 more
openaire   +2 more sources

Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes

Atherosclerosis, 2002
Monocytes and macrophages synthesize tissue factor (TF) which plays a role in thrombogenicity in coronary artery disease. This study was conducted to investigate the effect of Rho/Rho-kinase inhibition on the synthesis of TF in cultured human monocytes. 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins), C3 exoenzyme and Rho-
Kenji, Nagata, Toshiyuki, Ishibashi, Takayuki, Sakamoto, Hiroshi, Ohkawara, Joji, Shindo, Keiko, Yokoyama, Koichi, Sugimoto, Sotaro, Sakurada, Yoh, Takuwa, Shin, Nakamura, Tamio, Teramoto, Yukio, Maruyama   +11 more
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The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI

Nature Neuroscience, 2003
The neurotrophin receptor p75(NTR) is involved in the regulation of axonal elongation by neurotrophins as well as several myelin components, including Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMgp). Neurotrophins stimulate neurite outgrowth by inhibiting Rho activity, whereas myelin-derived proteins activate ...
Toshihide, Yamashita, Masaya, Tohyama
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QCD factorizations in gamma* gamma* -> rho rho

2006
We calculate the lowest order QCD amplitude, i.e. the quark exchange contribution, to the forward production amplitude of a pair of longitudinally polarized $ρ$ mesons in the scattering of two virtual photons $γ^*(Q_1) γ^*(Q_2) \to ρ^0_L ρ^0_L$. We show that the scattering amplitude simultaneously factorizes in two quite different ways: the part with ...
Pire, B., Segond, M., Szymanowski, L., Wallon, S.   +3 more
openaire   +1 more source

Rho Transcription Factor:  Symmetry and Binding of Bicyclomycin

Biochemistry, 2000
The antibiotic bicyclomycin inhibits rho-dependent termination processes by interfering with RNA translocation by preventing RNA binding at the translocation site or by uncoupling the translocation process from ATP hydrolysis. Previous studies have shown that bicyclomycin binds near the ATP hydrolysis pocket on rho.
F, Vincent, M, Openshaw, M, Trautwein, S J, Gaskell, H, Kohn, W R, Widger   +5 more
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Metal Dependency for Transcription Factor Rho Activation

Biochemistry, 2003
The Escherichia coli rho transcription termination factor terminates select transcripts and rho activity requires Mg(2+). We investigated whether divalent metal ions other than Mg(2+) catalyze rho-dependent ATP hydrolysis to ADP and P(i) in vitro. The effects of 11 divalent metal ions (Be(2+), Ca(2+), Cd(2+), Co(2+), Cu(2+), Hg(2+), Mn(2+), Ni(2+), Sr ...
Thomas P, Weber, William R, Widger, Harold, Kohn   +2 more
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Autogenous regulation of transcription termination factor Rho

Journal of Molecular Biology, 1985
We present evidence that the transcription termination factor Rho is autogenously regulated in Escherichia coli. The steady-state level of Rho is increased approximately tenfold in rho mutant cells. In the rho+ revertants, the content of Rho is similar to the wild-type level. A rho-/rho+ merodiploid produces equimolar amounts of the mutant and the wild-
S, Barik, P, Bhattacharya, A, Das
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Mastering the control of the Rho transcription factor for biotechnological applications

Applied Microbiology and Biotechnology, 2021
The present review represents an update on the fundamental role played by the Rho factor, which facilitates the process of Rho-dependent transcription termination in the prokaryotic world; it also provides a summary of relevant mutations in the Rho factor and the insights they provide into the functions carried out by this protein.
Tomás G. Villa, Ana G. Abril, Angeles Sánchez-Pérez   +2 more
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A new inhibitor of the transcription–termination factor Rho

Biochemical and Biophysical Research Communications, 2003
In this study we describe BI-K0058, a new inhibitor of the transcription-termination factor Rho belonging to a different chemical class from bicyclomycin, the only known antibiotic acting on Rho. BI-K0058 inhibits the poly(C)-dependent ATPase activity of Rho with an IC(50) of 25 microM as well as in vitro transcription-termination of two natural ...
CARRANO L, ALIFANO, Pietro, CORTI E, BUCCI, Cecilia, DONADIO S.   +4 more
openaire   +3 more sources

Parallelization of Pollard's Rho Integer factorization algorithm

Proceedings of the Second International Conference on Computational Science, Engineering and Information Technology, 2012
In the new era of computing technology, demands legacy algorithms to be adaptable to everchanging hardware architecture. With advent of higher processing capablities, the legacy algorithms needs to be re-designed to suit the state-of-art computing methods to yield maximum and effective utilization of resources.
G. Harish, G. Punith Kumar, Anjan K. Koundinya, Y. V. Pramod, N. K. Srinath, G. E. Raghavendra Kumar, R. Sandeep, Archit Shukla, Madan Acharya   +8 more
openaire   +1 more source